You're Tearing Me Apart
In this inherited connective tissue disorder, defective fibrillin-1 weakens the aortic wall, increasing dissection risk.
What is Marfan syndrome?
These are the 2 classification systems for aortic dissection.
What is Stanford and DeBakey?
This enzyme, elevated in the blood, is the most sensitive marker of muscle injury.
What is creatine kinase (CK)?
This class of medications is used as the first-line treatment to reduce blood pressure and prevent further dissection.
What are beta-blockers?
This phenomenon can lead to patients with legitimate pain being dismissed, often due to previous drug-seeking behavior.
What is the "boy who cried wolf" effect?
Aortic dissection leads to this type of channel within the wall of the aorta, which may compromise true lumen perfusion.
What is a false lumen?
In the Stanford system, Type A dissections always involve this section of the aorta.
What is the ascending aorta?
These two common electrolyte abnormalities are seen due to cell breakdown and release.
What are hyperkalemia and hyperphosphatemia?
This drug, often used alongside beta-blockers, helps manage blood pressure in aortic dissection by dilating blood vessels.
What is nitroprusside?
This action, when taken by a healthcare provider, can sometimes result from bias, and involves withholding pain medications from patients who may be at risk of substance use disorder.
What is undertreatment (or withholding pain medications)?
This type of necrosis, often seen in connective tissue disorders, weakens the aortic media
What is cystic medial degeneration?
In the DeBakey system, this type starts in the ascending aorta and extends into the descending and beyond.
What is Type I?
See Notes
Rhabdomyolysis can be caused by extreme physical exertion, trauma, or this class drug (there are a few --> relavent to this course please.
What are statins?
will accept Fibrates, Antipsychotics, SSRIs, Stimulants, Anesthetics / Muscle Relaxants, Antivirals, Alcohol and Illicit Drugs
If a patient has an acute type A dissection, this is typically the recommended treatment.
What is urgent surgical repair?
This bias occurs when a patient with a history of substance abuse or psychiatric illness is seen as less credible, leading to poorer care or missed diagnoses.
What is confirmation bias?
Dissections involving this major abdominal vessel can lead to mesenteric ischemia and bowel infarction.
What is the superior mesenteric artery?
In DeBakey Type III dissections, the tear originates here.
What is the descending aorta (usually distal to the left subclavian artery)?
This is usually administered IV and is the first-line for treatment of rhabdomyolysis
What is isotonic saline (normal saline)?
In cases of Type B aortic dissection, this is often present that indicates surgery.
What are symptoms?
This symptom of aortic dissection, often described as "tearing" or "ripping," can sometimes be misinterpreted as psychosomatic in patients with a psychiatric history.
What is chest pain?
In aortic dissection, asymmetric pulses or blood pressure differences between limbs indicate involvement of these vessels
What are the subclavian or brachiocephalic arteries?
The Stanford classification splits aortic dissections into these two types.
What are Type A and Type B?
Describe them to me for 1 Trillion Points
This life-threatening condition caused by muscle swelling can cause and result from rhabdomyolysis.
What is compartment syndrome?
See Notes
This is a common complication specific to Stanford Type A dissection and this Tx that it requires to alleviate Sx.
give me the common complication and Tx.
will accept multiple answers.
What is pericardial tamponade with pericardiocentesis?
What is coronary artery involvement and CABG?
A patient with a history of anxiety and chronic pain and severe chest or back pain, this is the first thing you should do.