Sight of action
Mechanism of action
Adverse effect & complications
Clinical use
100

What was the memory trick to remember Diuretics?

Diuretics think dry inside 

100

How many stars are in the ppt?

17

100

What rare but serious condition can occur as a complication of certain diuretics, related to the pancreas?

A) Metabolic alkalosis
B) Gout
C) Pancreatitis
D) Ototoxicity  


C-Pancreatitis

100

Who Was the first person to invent thiazide diuretics?


Frederick Novello


200

Where do thiazide diuretics primarily exert their action?

  • A) Proximal convoluted tubule
  • B) Loop of Henle
  • C) Distal convoluted tubule
  • D) Collecting duct

C-Distal convoluted tubule

200

Which of the following diuretics increases sodium and water excretion by inhibiting the enzyme carbonic anhydrase? A) Thiazide diuretics
B) Loop diuretics
C) Carbonic anhydrase inhibitors
D) Potassium-sparing diuretics  


C- Carbonic anhydrase inhibitors

200

What was the joke that was told on the first slide?

Full points if you can tell the joke Correctly .

Half the points if you get a portion of it correct.

Why did the computer go to the pharmacy?

It had a virus!


200

Which of the following is a common clinical use of diuretics? A) To increase blood sugar levels
B) To eliminate excess fluid
C) To stimulate appetite
D) To enhance muscle growth  


B-To eliminate excess fluid

300

Potassium-sparing diuretics, such as spironolactone, act on which part of the nephron?

  • A) Proximal convoluted tubule
  • B) Loop of Henle
  • C) Distal convoluted tubule
  • D) Collecting duct

D-collecting duct

300

Which mechanism of action is characteristic of thiazide diuretics? A) Inhibition of sodium reabsorption in the collecting duct
B) Inhibition of carbonic anhydrase in the proximal tubule
C) Inhibition of sodium reabsorption in the distal convoluted tubule
D) Blocking the reabsorption of urea in the loop of Henle

C-Inhibition of sodium reabsorption in the distal convoluted tubule

300

Which condition is characterized by a drop in blood pressure when standing, and is a possible adverse effect of diuretics?

A) Hyperglycemia
B) Orthostatic hypotension
C) Dehydration
D) Gout  

B-Orthostatic hypotension

300

Diuretics are often used in the management of which of the following conditions? A) Hypotension
B) Congestive heart failure
C) Asthma
D) Osteoporosis  


B-Congestive heart failure

400

Which diuretic class is most effective in treating edema due to heart failure and works at the site of action in the thick ascending limb of the loop of Henle?

  • A) Osmotic diuretics
  • B) Thiazide diuretics
  • C) Loop diuretics
  • D) Carbonic anhydrase inhibitors

C-loop diurectics

400

In what way do potassium-sparing diuretics primarily function?

A) By directly inhibiting sodium reabsorption in the loop of Henle
B) By antagonizing aldosterone at the collecting duct
C) By blocking Na+/Cl- reabsorption in the proximal tubule
D) By increasing renal blood flow and GFR  


B-By antagonizing aldosterone at the collecting duct

400

Which electrolyte imbalance is known to potentially lead to serious cardiac arrhythmias when caused by diuretics?

A) Hypercalcemia
B) Hyponatremia
C) Hypokalemia
D) Hypomagnesemia  


C- Hypokalemia

400

Which class of diuretics is primarily used in the management of hypertension and heart failure due to their effectiveness in reducing fluid volume? A) Potassium-sparing diuretics
B) Thiazide diuretics
C) Loop diuretics
D) Carbonic anhydrase inhibitors  

B- Thiazide diuretics

500

Which mechanism of action characterizes the carbonic anhydrase inhibitors, such as acetazolamide, and where do they predominantly act in the nephron?

  • A) Inhibition of sodium reabsorption; proximal convoluted tubule
  • B) Inhibition of sodium-potassium pumps; distal convoluted tubule
  • C) Inhibition of chloride-sodium symporters; loop of Henle
  • D) Inhibition of aldosterone; collecting duct

A-Inhibition of sodium reabsorption;proximal convoluted tubule

500

CONGRATULATIONS!!!!!

You get to steal 100 points from the opposite team!!!!!!!!

500

What is a potential effect of high doses of loop diuretics that pertains to hearing?

A) Hyponatremia
B) Ototoxicity
C) Hyperglycemia
D) Hypomagnesemia  


B-Ototoxicity

500

In the context of pharmacology, which diuretic is specifically indicated for the treatment of acute pulmonary edema due to its rapid onset of action and the ability to produce significant diuresis? A) Hydrochlorothiazide
B) Spironolactone
C) Furosemide
D) Bumetanide  


B-Furosemide