DKA
HHS
Management of DKA & HHS
100

Early signs of DKA

Polyuria, polydipsia, Kussmaul respirations, fruity breath, fatigue, nausea & vomitting

100

What lab is most elevated in patients with HHS?

What is blood glucose levels often reaching > 600 mg/dL. 


100

What needs to be done before turning off an insulin infusion? 

What is, give Sub Q insulin 2 hours before turning off the insulin infusion?  


200

This lab value confirms the resolution of DKA more accurately than blood glucose

What is, closure of anion gap?



200

What are common triggers for HHS?

What is infection, poorly controlled type 2 diabetes, steroids, trauma, surgery, and poor oral intake 

200

What significant DKA lab(s) or hemodynamic abnormalities require ICU admission?

What is, a bicarb <10, Acidosis, Respiratory Distress, hypotension, altered mental status. 

300

Describe the basic pathophysiology of DKA

What is, no Insulin production- cells are starving- fat breakdown- liver converts fats into Ketones-Metabolic Acidosis 
300

what is the most important initial intervention in HHS? 

What is aggressive IV fluid administration due to high fluid volume loss. 

300
What life threatening Reaction can occur if glucose is corrected to rapidly?

What is Cerebral edema?

400

A PaCO2 of 25 mmHg in a DKA patient reflects this physiologic response? 

What is respiratory compensation?


400

Unlike DKA, HHS does not present with this initial metabolic finding

What is, Ketosis?

400

What is the goal rate of decreasing blood glucose within an hour?

What is 50-75 mg/dL per hour?

500

A patient’s glucose is 240 mg/dL, anion gap is still elevated, and potassium is 3.8. The priority nursing action is? 

What is switch to D5W and NaCL 0.45% infusion if blood glucose < 250 mg/dL.


500

Describe the basic pathophysiology of HHS?

What is, a small amount of insulin is present- persistent hyperglycemia- osmotic diuresis- severe dehydration- leads to neurological dysfunction, electrolyte abnormalities, hypotension, tachycardia etc. 

500

ICU Insulin Infusion order set VS DKA/HHS insulin Infusion order set

The ICU insulin infusion order set requires only a TKO fluid order and is units/hr, whereas the DKA/HHS insulin infusion order set is units/kg/hr and requires either 0.45% naCL at a rate of 125 mL/hr or D5W & 0.45% once blood glucose , 250 and titrated per hourly BS.