Depressive Disorders
MDD (in more detail)
Bipolar Disorder
Bipolar Disorder Treatment / pharmacology
pharmacology continued
100
what are depressive disorders and what are the 2 types we discussed in class ? 

depressive disorders all share symptoms of sadness, emptiness, irritability, somatic concerns, and impairment of thinking and all impact a persons ability to function 

the 2 we discussed are Disruptive mood dysregulation disorder and MDD 

100

explain the diagnosis component of MDD in the nursing process 

risk for suicide is the HIGHEST PRIORITY !, chronic low self esteem, imbalanced nutrition, constipation, disturbed sleep pattern, ineffective coping, disabled family coping 

100

what are the different types of bipolar disorder ? 

Bipolar 1 = most severe, at least 1 manic episode 

Bipolar 2 = at least 1 hypomanic and 1 MDD episode 

Cyclothymic disorder = symptoms of mild-mod depression for at least 2 years, rapid cycling possible 

100

what kinds of therapy do we recommend with bipolar disorder ? 

CBT - in adjunt to pharm 

interpersonal and social rhythm therapy - aims to regulate social routines and stabilize interpersonal relationships to improve depression and prevent relapse 

family focused therapy - helps improve communication among members 

200

explain DMDD (when is it diagnosed, symptoms, management) 

- diagnosed in children ages 6-18 

symptoms : constant/severe irritability and anger, tantrums out of proportion to the situation ( > 3x a week), exhibits symptoms in at least 2 settings

management : symptomatic medications, CBT, parental training, facial expression recognition training 


200

what model do we use for outcomes with MDD and what do we focus on with planning ? 

recovery model - focus on patients strengths, treatment foals mutually developed, based on PATIENTS personal needs/values 

planning is geared towards their phase of depression, symptoms, and personal goals 

200

explain the difference between hypomanic episodes and manic episodes 

hypomanic - a low level of mania, tends to be euphoric and often increases functioning, usually accompanied by excessive activity and energy 

manic - worse level of hypomania 

200

explain SSRIs 

med - prozac, lexapro, zoloft 

indications - MDD, BP, PD, OCD, bulimia nervosa 

AE - insomnia, anxiety, sexual dysfunction, n/v, weight gain, dry mouth, hyponatremia, SI, serotonin syndrome 

NC - morning med, 4-6 weeks for effectiveness, contraindicated with MAOIs, increase in suicidal thoughts, hyperactivity/tachy should be reported, stopping it abruptly can lead to discontinuation syndrome 

300

with MDD... what are most common co-mo, and what is are the requirements to be diagnosed 

co-mo : anxiety and depression 

requirments (per DSM5) - 

5 or more in a two week period : weight and appetite changes, sleep disturbances, fatigue, worthlesness or guilt, loss of ability to concentrate, reccurent death thoughts, psychomotor agitation 

PLUS at least 1 symptom of depreesed mood or loss of interest/pleasure, persistent for 2 weeks-6 months (chronic = > 2 years), recurrent episodes common, symptoms cause distress/impaired function, and an absence of a manic or hypomanic episode 

300

how should we communicate with these patients when forming a plan of care ? what do we need to implement for their care ? 

make sure to use simple concrete words and allow time for a response, make sure to listen for covert messages and directly ask about SI and avoid platitudes. 

make sure to implement counseling/communication, health edu/promotion, promotion of self care, and teamwork/safety 

300

explain the RF as well as why someone with BD may have to be hospitalized 

RF = genetics, neurobiological factors, neuroendocrine, and peripheral inflammation as well as our typical environmental and cognitive factors 

Hospitalization : Hospitalization for suicidal, psychotic, or catatonic signs, depressive episodes, or Medication concerns about bringing on a manic phase

- Provides safety for a person experiencing acute mania

- Imposes external control on destructive behaviors

- Provides medication for stabilization

300

explain SNRIs 

med - effecxor 

indications - MDD, social anxiety, GAD 

AE - nausea, HTN 

NC - morning med, 4-6 weeks, contraindicated with MAOIs, increased SI, take with food for GI upset, monitor BP 

400

discuss the risk factors for MDD 

biological : genetic (1st degree), biochemical, hormonal, inflammatory, diathesis stress model (genetic and biological)

cognitive : females more than males, adverse childhood events, substance abuse, anxiety, personality disorders, chronic or disabling medical conditions 

400

what are the various treatment options for patients with MDD ? 

- antidepressants, integrative medicine (st. john's wort), brain stimulation therapy, light therapy, and exercise. 

- therapies include CBT, interpersonal therapy, and time limited focused psychotherapy  

400

what kind of thought processes, speech patterns, and thought content might these patients present with ? why is this important with cognitive dysfunction ? 

- pressured, circumstantial, or tangential speech 

- loose associations or flight of ideas 

- grandiose or persecutory delusions 

these are important because they affect patients overall function with mania and chronicity of illness 

400

explain TCA 

med - amitriptyline 

indication - MDD 

AE - sedation, anticholinergic effects, postural htn, increased SI, lethal if OD 

NC - monitor ortho VS, dont stop abruptly or take with MAOIs, bedtime med, urinate before daily dose, increase fiber and fluids, dry mouth !, caution in elderly with cardiac disease 

400

explain mood stabilizers 

med - Lithium carbonate 

indications - acute mania, bipolar 

AE - GI, muscle weakness, drowsy, HA, confusion, polyuria, tremor, goiter and hypothyroidism

NC - monitor for toxic levels (should be < 1.0), monitor sodium, take with food or milk, stop taking and alert MD if you have hand tremors, diarrhea, or vomiting, and expect to gain 5 lbs of water weight in the first week  

500

what are the ways we assess for someone with MDD 

- suicide assessment 

- self assess 

- behavior and affect 

- mood, emotions, thoughts/perceptions, co-mo 

500

explain the different types of brain stimulation therapies with MDD 

ECT : most effective, primary treatment in severe malnutrition exhaustion or dehydration, safer than meds with some conditions, delusional depression, failure with other meds, and schizophrenia with catatonia 

RTMS : MRI strength magnetic pulses stimulate focal areas of the cerebral cortex ; AE = HA, lightheaded, seizures (rare), scalp tingling 

VNS : electrical stimulation boosts the level of neurotransmitters (can cause voice alterations, neck pain, cough, paraesthesia, and dyspnea 

DBS : surgically implanted electrodes in the brain that stimulate the regions that are under active in depression 

500

what kind of communication techniques will we use with these patients ? 

- firm and calm approach 

- short and concise explanations 

- identify expectations in simple, concrete terms 

- hear and act on legitimate complaints 

- firmly redirect energy to more appropriate channels 

500

explain MAOIs 

med - phenelzine (nardil) 

indications - depression not responding to other meds 

AE - ortho htn, HTN crisis, insomnia, N/V, SI, agitation, constipation 

NC - foods with tyramine must be eliminated, maintain restrictions for 2 weeks after stopping meds, avoid caffeine, stimulants, or OTC cold meds, dont stop abruptly, ER if severe HA occurs, monitor BP, contraindicated with cardiac, liver, renal disease, or > 60 y.o. 

500

explain anticonvulsants 

med - valproic acid (depakote, depacon, depakene) 

indications - mania 

AE - bruising, prolonged bleeding times, GI symptoms, liver toxicity, neural tube defects, skin rash, pancreatitis 

NC - monitor bleeding time and platelet count, report bleeding, bruising, rash, jaundice, n/v, take with food