History
Captured "photo 51" using X-ray crystallography
Rosalind Franklin
Double Helix
When does DNA replication occur? (within the cell cycle)
Interphase
Enzyme that "unzips" the original DNA molecule by breaking apart base pairs
Helicase
DNA stands for:
Deoxyribonucleic Acid
Erwin Chargaff confirmed that:
The monomer of nucleic acids:
nucleotide
What direction does DNA replication occur from the perspective of the new, complementary strand?
5' to 3'
Enzyme that acts as the "builder" of the new molecules of DNA by adding complementary base pairs
DNA Polymerase
Replicate the following strand of DNA:
ATTTCGCTAGCCA
TAAAGCGATCGGT
In "My" experiment, mice were injected with variations of virulent and non-virulent bacterial strains
Griffith
Double ringed nitrogen bases (Adenine and Guanine)
Purines
DNA is "antiparallel". What does that mean?
Strands oriented in opposite directions (5' to 3' and 3' to 5')
What does DNA Ligase do in the process of DNA replication?
Fills in the cracks and seals together newly replicated molecules of DNA
A virus that specifically infects bacterial cells
Bacteriophage
Oswald Avery and his team isolated major molecules in bacterial cultures previously used in other experiments and observed this genetic principle:
Transformation
The (4) nitrogen bases that make up molecules of DNA:
Adenine, Guanine, Cytosine, Thymine
DNA Replication is "Semi-Conservative". What does this mean?
newly replicated molecules of DNA are 50% original/template and 50% new/complementary
Enzyme that builds and lays down the "Primer" to initiate the replication process
Primase
Which nitrogen base is in RNA that is not contained in DNA?
Our team confirmed that DNA, and not protein, was the "transforming" principle by measuring radioactively labeled isotopes in different parts of bacterial viruses.
Hershey and Chase
The (3) components of a nucleotide:
Nitrogen Base, 5-carbon sugar, and a phosphate group
What are the 3 Phases of DNA Replication?
Initiation, Elongation, and Termination
What does Topoisomerase do within DNA replication?
unwinds original DNA molecule and controls rate of replication
The short segments of replicated DNA in the lagging strand are known as_________________________.
Okazaki Fragments