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History of DNA
DNA Structure
DNA Replication
Miscellaneous
100
DNA-(TRANSCRIPTION)->pre mRNA (RNA processing)->mature mRNA-(TRANSLATION)->protein
Central Dogma of Biology
100
3 parts: phosphate, sugar, nitrogen base
What is a nucleotide
100
The location of DNA replication
What is the NUCLEUS
100
The difference between Replication Fork- and Origin of Replication
Replication Fork= the base of separation of the 2 strands (moves in a 5' to 3' direction) Origin of Replication = Location that DNA Polymerase begins (will be different on lagging and leading strands)
200
mice and R and S strain; maybe transformation?
Griffith
200
Complementary base pairing means?
A-T G-C
200
The 1st step in replication is 1. _____________ caused by the enzyme 2. ______________.
1.Unwinding of 2 strands by breaking hydrogen bonds between bases 2.Enzyme: Helicase
200
Direction of replication is __________
5' to 3'
300
made 3D model of DNA structure
Watson & Crick
300
The different strands in the helix run in opposite directions
Antiparallel: One strand is 5' to 3'. The complementary strand is 3' to 5'.
300
small segments of replicated DNA formed on the lagging strand
What is Okazaki fragments
300
Glues Okazaki fragments together
Ligase
400
Created base pairing rule
Chargaff
400
Write the complementary DNA strand: A-T-G-C
T-A-C-G
400
One old strand and One new strand
What is the SEMI-CONSERVATIVE MODEL of DNA replication
400
x-ray diffraction images of DNA
Franklin & Wilkins
500
DNA/Protein mixtures of R and S strain (transforming principle exists)
Avery, McCleod, McCarty
500
Nitrogen bases are grouped into what 2 types of ringed structures?
What are purines (2 rings)- A & G What are pyrimidines (1 ring)- T & C
500
Adds DNA nucleotides
What is DNA Polymerase
500
Used bacteriophages; DNA is definately genetic material
Hershey & Chase