Proteins
What protein's job is to unzip DNA?
Helicase
The majority of humans have ______ chromosomes.
46
Nucleic acids form pairs, what nucleic acids pair up?
A-T
C-G
What is a complementary strand?
Complementary strands are mirror images of one another
Why can’t the lagging strand be built continuously?
It is in the wrong direction (3'-5') so we must build it "backward"
Name the protein that is responsible for laying down nucleic acids (building the daughter strand) and checking for mutation.
DNA Polymerase
We say that DNA has a ____________________ structure.
double helix
If we think of DNA as a ladder what are the “legs” made out of?
phosphate backbone
Complimentary DNA strands run ____________________________ to one another.
antiparallel
DNA Polymerase can only build DNA in which direction?
5'-3'
The job of Topoisomerase (DNA Gyrase) is...
prevents supercoiling (prevents DNA from becoming a tangled mess)
A mutation is...
a change to the DNA sequence
What holds complementary strands of DNA together?
Hydrogen bonds between nucleic acids
The site where DNA has been unwound and replication is taking place is called...
Replication Fork
What strand is built in the 5'-3' direction?
Continuous strand
What is the job of DNA Ligase?
"Glue" segments of DNA back together
What are primers made out of?
RNA
If we think of DNA as a ladder what would the “rungs” be made out of?
Nucleic acids (base pairs) (A,C,T,G)
A repeating sequence of nucleic acids that tell the cell where to begin DNA replication is called what?
The origin of replication
What is RNA primases job in DNA Replication?
To lay down RNA primers for DNA Polymerase to build off of
What is the complementary strand of DNA for the section below?
5'-GCCGAATA-3'
3'-CGGCTTAT-5'
The model describes how DNA replicates?
Semiconservative model
The strand that is built using okazaki fragments is called the...
lagging strand