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Five
100
DNA replication makes a _______ copy of the two strands.
Complementary
100

How DNA is prioritized for replication?

first acetylated DNA with active transcription

100
Enzyme that nicks and unwinds strands to release mechanical stress of unwinding
Topoisomerase
100

What is the prereplication complex in eukaryotes?

The recognition of the autonomous replication site by the ORC protein attracts the MCM 2-7 proteins that, after being phosphorylated, begin to separate the double chain to form the replication fork.

100
What is the strand that replicates continuously
Leading strand
200
DNA replication is ____conservative
semi
200
What is the main enzyme used in replication?
DNA Polymerase
200
Enzyme that unwinds DNA at the replication fork
Helicase
200
What is another name for topoisomerase?
Gyrase
200
What is the stranded that replicates in pieces
Lagging strand
300
Replication is mediated by what enzyme?
DNA polymerase
300

Subunit that allows the polymerase to move through the parental DNA?


beta clamp

300
Enzyme that initiates new strand synthesis
RNA Primase
300

DNA polymerase runs along the template DNA in the direction:

3' -- 5'

300
What are the pieces of the Lagging strand also called?
Okazaki Fragments
400
Replication proceeds in the ______ direction
5' to 3'
400
Where does replication start?
Ori site, origin of replication
400
What stabilizes single stranded DNA at replication fork?
Single stranded binding proteins (SSB Proteins)
400
site where DNA strands separate to initiate replication
Replication Fork
400
Telomeres _____ with age
shorten
500
In replication, the ____ strand serves as a template to the ____ strand
parental, daughter
500
DNA strands replicate ___directionally
bi
500
enzyme that joins okazaki fragments on lagging strand
DNA Ligase
500
Initiation takes place ______ at different sites
simultaneously
500
Telomerase resets chromosome ends in embryos. Why is it controlled later in life?
Cancer