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Structure and Function of DNA
DNA Replication
RNA and Transcription
Protein Synthesis
Mutations
100
One DNA strand has a base sequence GTCCATA. The base sequence on the second strand of DNA is...
CAGGTAT
100

What does the word "replicate" mean? During what phase of the cell cycle does DNA replication take place?

To make an identical copy.... S-phase

100
A single stranded piece of a DNA has the following bases: ACTGAG. What is the matching sequence on its RNA transcript?
UGACUC
100
This process turns mRNA into a protein.
Translation.
100
What is a mutation? Name 2 environmental factors can cause a mutation.
Any change to an organism's DNA/genome. Environmental factors: chemicals, radiation, sun, food, & viruses
200
What do we call the monomers of DNA? What are its 3 parts? Which two parts form the backbone? What is the function of the backbone?
Nucleotide: phosphate group, sugar (deoxyribose), base (A, C, T, or G). The phosphate and sugar form the backbone. The backbone provides structure and support for the molecule.
200
What is the end product of DNA replication (be very specific!)
Two new molecules of DNA, each is identical to each other and to the original molecule.
200

Transcription: What does is make? Where does it take place? And identify the base pair rules used

RNA. Nucleus.

A-U 

C-G 

200
What cell organelle makes protein? What are the monomers of protein called?
Ribosome / amino acids
200
What is a frameshift mutation?
This type of mutation occurs when bases are inserted or deletedm, causing ALL the codons from the point of mutation forward to change, thus change causing all the amino acids to change.
300
Describe the function/purpose of DNA in organisms. What is a gene?
A gene is a sequence of DNA nucleotides that acts as a recipe for a specific protein.
300

Name the two enzymes involved in DNA replication?

Helicase: unzips/unwinds the DNA helix by breaking the bonds between the bases. DNA polymerase: makes DNA by adding complementary bases to the other side of each of the original strands.

300
Why can’t DNA leave the nucleus?
DNA is too long/bulky to exit through the nuclear pores.
300
What is an anti-codon? What is its purpose?
A 3 nucleotide sequence on a tRNA that matches to a specific mRNA codon. When a tRNA finds a matching mRNA codon (with the ribosomes help), it drops off the attached amino acid to be used in protein.
300

A mutation that codes for a stop codon too early in the sequence. 

Nonsense mutation 

400

These two processes happen in the nucleus involving DNA. 

What are DNA Replication & Transcription

400
Why does DNA need to be copied?
So that when the cell divides, each new cell has a complete set of DNA.
400
Name the three different types of RNA and describe the function of each of them.
mRNA: delivers a copy version of a DNA gene from the nucleus to the ribosome. tRNA: transfers the amino acids to the ribosome. rRNA: part of the ribosome.
400
A ribosome makes a protein containing 60 amino acids. The corresponding mRNA consists of at least how many codons?
60
400
This type of mutation is the most dangerous... Explain Why 

Frameshift 

500
In a sample of DNA, 40% of the bases are adenine. What percentage of bases are guanine?
10%
500
Why is DNA replication called a "semi-conservative" process?
DNA replication is "semi-conservative" because each new molecule of DNA has one original strand and one newly synthesized strand (it is half conserved, or half saved)
500
Name 4 differences between DNA and RNA.
DNA: deoxyribose, thymine, long, double-stranded, made by DNA replication. RNA: ribose, uracil, short, single-stranded, made by transcription.
500
1) The bonds that the ribosomes use to hold amino acids together during protein synthesis are called… 2) This is what we call a chain of amino acids (a protein before it gets its shape)
Peptide bonds. Polypeptide.
500

The original strand of DNA is ACT TTG CGA The mutated strand of DNA is ACT TTC GA This is a _______________ mutation that causes a _________ of amino acids.


Deletion..... Frameshift