At which stage of the Cell Cycle does DNA Replication occur?
S phase (Interphase)
What does Primase do?
the 5' end of a DNA strand ends with which functional group?
phosphate
which is the correct model for DNA replication?
semiconservative
Which type of bonds are broken by Helicase?
hydrogen bonds.
On the lagging strand, in which direction does DNA polymerase move down the template with respect to the fork?
the opposite direction
which scientists tested the 3 models of DNA replication?
What enzyme is essential for joining the Okazaki fragments?
Ligase
what stabilized the single-stranded DNA after it is unwound?
ssBPs (single stranded binding proteins)
which type of bond joins the deoxyribose to the nitrogenous base?
glycosidic
which organism was used in the meselson and stahl experiment?
bacteria (E. coli)
What does topoisomerase do?
relieves the tension created by unwinding the helix
is primase needed in order to make the leading strand, lagging strand, or both?
both
which functional group is found on the 3' carbon of deoxyribose?
hydroxyl
Which scientist(s) proved that the Transforming Factor was DNA?
Avery and Macleod
Which term describes the direction of the two DNA strands with respect to each other?
Anti-Parallel
primase
where on the chromosome does DNA replication begin?
the origin of replication
what do you call two replication forks joined together?
a replication bubble
Which scientists used bacteriophage and bacteria in order to show that DNA is the hereditary molecule?
Hershey and Chase