MOA
What is the MOA of Carbamazepine?
Sodium channel blocker
Ethosuximide is used for what type of seizure?
Absence seizures
Which anti-seizure medication is a controlled substance?
Barbiturates
Which drug can cause gingival hyperplasia?
Phenytoin
How do barbiturates affect the GABA receptors?
Increases the duration of the opening
Prolonged chloride channel opening
Which anti-seizure drug's brand name is Keppra?
Levetiracetam
Gabapentin is used for what other conditions (2)?
Restless leg syndrome, postherpetic neurlagia
Valproate use during pregnancy can cause what neurologic condition?
Spina bifida
What is the MOA of Gabapentine?
Blocks calcium channels
What medication is used to treat a benzodiazepine overdose?
Flumazenil
What happens when valproate and lamotrigine are taken together?
Valproate reduces the clearance of lamotrigine -> toxicity
Which anti-seizure drug can cause kidney stones?
Topiramate
How do benzodiazepines affect the GABA receptors
Increases the frequency of channel opening
Which drug has a nonlinear pharmokinetics?
Phenytoin
Which type of seizures can carbamezapines exacerbate?
Absence seizures
Levetiracetam can cause what type of psychiatric AE
What is the postulated MOA of Levetiracetam?
SV2A binding -> decrease in neurotransmitter release
Topiramate also acts as what other type of innhibitor?
Carbonic anhydrase inhibitor
Carbamazepine can cause what type of dermatologic side-effect?
SJS