Imaging to distinguish different subtypes of cardiac amyloid
99m-Technetium pyrophosphate scintigraphy
AKI, fever, rash, eosinophilia
Acute interstitial nephritis
ID the lesion
Superficial spreading melanoma (accept Melanoma)
an exaggerated inflammatory skin reaction to minor, non-specific trauma, most notably seen in patients with which pathology?
Behcet syndrome
Most common cause of acute liver failure
What is Acetaminophen overdose?
Wolff-Parkinson-White syndrome first-line treatment
Catheter ablation
Hemoglobin threshold for ESA in CKD
Hemoglobin < 10g/dL
Patient was carrying weights and heard a popping sound. Identify the sign and cause.
Popeye sign
Biceps tendon rupture
A 60-year-old man presents with symmetric proximal muscle weakness, elevated CK, and interstitial lung disease. His labs show positive anti-Jo-1 antibody. What additional imaging should be performed?
CT chest for lung cancer screening
CT findings of retroperitoneal fibrosis and sausage shaped pancreas are characteristic of this etiology of pancreatitis.
What is Type 1 Autoimmune pancreatitis /IgG4 disease?
What is WPW syndrome ?
ID the lesion and underlying genetic condition associated with angiomyolipomas that often transforms to renal cell carcinoma later in life.
Shagreen Patch
Tuberous sclerosis
POCUS of lung - ID pathology
PTX
A 45-year-old man presents with sinusitis, otitis media, hematuria, and cavitary pulmonary nodules. What is the most likely autoantibody, and what specific antigen does it target?
c-ANCA (anti–proteinase-3 antibody)
A normal MR cholangiopancreatography and presence which antibody is diagnostic of Primary Biliary Cirrhosis?
What is AMA?
Imaging test for suspected arrhythmogenic RV cardiomyopathy/dysplasia
Cardiac MR imaging
A cirrhotic patient with ascites develops rising creatinine despite volume repletion. Urine sodium is low, and there is no evidence of structural kidney disease. What is the underlying pathophysiologic mechanism of this pathologic process?
Portal hypertension → splanchnic arterial vasodilation (mainly via nitric oxide) → ↓ effective arterial blood volume → compensatory renal vasoconstriction (via RAAS, SNS, vasopressin) → renal injury
ID lesions
Necrobiosis Lipoidica
A 55-year-old RA patient on methotrexate develops fever, hypoxia, and bilateral ground-glass opacities. Infectious work-up is negative. What is the most likely diagnosis?
Methotrexate-induced pneumonitis
A patient with pill-induced esophagitis has chest pain and odynophagia. Which medications are most classic culprits? Name 3 classes at least.
Tetracyclines, bisphosphonates, NSAIDs, potassium chloride, iron supplements.
Most common genetic conditions that require screening for aortic disease
Marfan and Ehlers-Danlos syndromes
A patient with membranous nephropathy has worsening proteinuria. Which autoantibody is most specific for idiopathic disease, and what malignancy screening should always be done?
Anti-PLA₂R antibody; screen for solid tumors (especially lung, colon, breast)
Patient comes in with rapidly progressive face lesion, after removing makeup, lesion is seen in images C and D. ID the lesion.
Discoid Lupus
A patient with RA develops shortness of breath and cough. HRCT shows a UIP pattern. Which RA autoantibody is most predictive of developing interstitial lung disease?
Anti-CCP
Age of onset and intervals for colorectal cancer screening in patients with familial adenomatous polyposis
Age 10 -12 years, Repeat colonoscopy every 1-2 years