Endocrinology and Metabolism
Genetics and Genomics
Cardiovascular Medicine
Women’s Health
Pulmonary
10

Enzyme deficiency characterized by virilization, hypotension, hyperkalemia, and cortisol deficiency

21-hydroxylase deficiency

10

Disease caused by beta-globin mutation leading to vaso-occlusion

Sickle cell disease

10

Cardiac syndrome with short PR interval, delta wave, and widened QRS complex

Wolff-Parkinson-White (WPW) syndrome

10

Non-contraceptive treatment for PMS and premenstrual dysphoria

Selective serotonin reuptake inhibitors (SSRIs)

10

Chronic lung disease of the major airways associated with cystic fibrosis

Bronchiectasis

20

Autoimmune skin condition associated with autoimmune adrenalitis

Vitiligo

20

Segment of a chromosome that shortens with aging

Telomere

20

FDA-approved antidote for oral factor Xa inhibitors

Andexanet alfa

20

Breast mass imaging modality for women younger than 30 years of age or who are pregnant

Ultrasonography

20

FEV1 value that defines GOLD 4 or very severe COPD

<30% of predicted (accept <30%)

30

Imaging study to detect extent and location of Paget disease of bone

Bone scintigraphy (accept radionuclide bone scan)

30

Hematologic malignancy associated with translocation of chromosomes 15 and 17

Acute promyelocytic leukemia

30

Imaging study with the highest negative predictive value for suspected cardiac sarcoidosis

Cardiac MRI (accept MRI)

30

Activity associated with decreased risk of breast, ovarian, and endometrial cancer

Breastfeeding

30

The two variables used to calculate the rapid shallow breathing index to assess readiness for weaning from mechanical ventilation

Respiratory frequency and tidal volume (accept respiratory rate)

40

Drug class used to treat amiodarone-induced thyroiditis type ll, or destructive thyroiditis

Glucocorticoids (accept steroids)

40

Ability of a mutation in a single gene to produce more than 1 phenotypic effect

Pleiotropy

40

Pathognomic finding of concentric ventricular wall thickness with low QRS voltage

Amyloidosis

40

Human papilloma virus type most highly associated with invasive cervical cancer

16

40

Pulmonary cause for cryptogenic stroke

Pulmonary arteriovenous malformations (accept PAVM, pulmonary shunt, or pulmonary arteriovenous fistula)

50

Rare complication of antithyroid drugs that presents as fever in 92% of cases

Agranulocytosis

50

Phenomenon in which successive generations display earlier or more severe manifestations of a genetic condition

Anticipation

50

Name for condition with low transvalvular pressures in patients with severe aortic stenosis but preserved left ventricular function

Paradoxical low-flow, low-gradient aortic stenosis

50

T-cell lymphoma associated with textured breast implants

Anaplastic large cell lymphoma (accept ALCL; ask for more specific detail if answer given is T-cell lymphoma)

50

Duration of treatment for cryptogenic organizing pneumonia

6 to 12 months (accept any time within this range)