Alc Help Me!
To Bleed or Not to Bleed
The Long and Winding COVID
Hello? Obturator?
Grantdora's Box
100

This enzyme is responsible for converting toxic alcohols into metabolic by-products to be eliminated in the urine.

What is alcohol dehydrogenase?

100

This trial is considered a cornerstone in the treatment of in-hospital symptomatic/severe anemia.

What is the TRICC trial? 

100

"Long COVID" is characterized as a multi-system disorder affecting patients who previously had COVID-19 with symptoms lasting at least this duration.

What is two months? 

100

This test is used to test stability of the ACL. 

What is the Lachman Test?

100

This two drug combination is approved for pre-exposure prophylaxis to HIV infection.

What is tenofovir and emtricitabine?

200

These tissue-resident macrophages in the liver are partly responsible for amplifying the auto-inflammatory response in alcoholic hepatitis.

What are Kupffer cells? 

200

This uncommon cause of [typically large volume] upper GI bleeding is characterized by a dilated, aberrant submucosal blood vessel that erodes through the overlying epithelium without an associated mucosal ulcer.

What is a Dieulafoy lesion? 

200

This term describes the phenomenon of persistent multi-system symptoms long after the initial infectious insult.

What is Post-Acute Infectious Syndrome [PAIS]?

200

This special test is nearly 92-93% sensitive/specific for lateral/medial meniscus tears. 

What is the Thessaly test?


200

This skin cancer type is the most prevalent in solid organ transplant patients.

What is squamous cell carcinoma?

300

Although with only an n of 55, this score is used in alcoholic hepatitis to predict 28-day mortality and guide steroid initiation

What is Maddrey Discriminant Function? 

300

The subcutaneous formulation of this drug has become an attractive option for patients with arteriovenous malformations with recurrent, uncontrolled bleeding and/or recurrent anemia.

What is octreotide?

Systemic Octreotide Therapy in Prevention of Gastrointestinal Bleeds Related to Arteriovenous Malformations and Obscure Etiology in Atrial Fibrillation. J Am Coll Cardiol EP. 2017 

Efficacy of pharmacologic treatment for treating gastrointestinal angiodysplasias-related bleeding: a systematic review and meta-analysis. Eur J Gastroenterol Hepatol. 2022 Oct 1;34(10):1021-1030.

300

This proposed pathophysiologic mechanism of Long COVID is a main reasoning behind the consideration of Paxlovid for treatment.

What is viral persistence?

300

The test shown below is used to assist with diagnosing tears of this tendon.

What is the subscapularis tendon?

300

This malignancy is the most common to be associated with celiac disease.

What is enteropathy-associated T-cell lymphoma (EATL)?

400

O for 2? The anti-inflammatory pentoxifylline, which inhibits this cytokine, was also found to be inferior to cilostazol for the treatment of claudication in addition to its inferiority to prednisolone for alcoholic hepatitis.

What is TNF-a?


400

Heyde syndrome is characterized by recurrent LGIB from AVMs in the setting of aortic stenosis from acquired deficiency of this molecule

What is von Willebrand factor? 


400

This trial offered support for post-discharge therapeutic anticoagulation in high risk COVID-19 patients.

What is the MICHELLE trial? 

400

Boettcher CE, et al found via EMG that the test shown in the figure activated this tendon up to 90% maximum voluntary contraction.

What is the supraspinatus tendon?

400

This is the name for antigen that does not require processing by antigen-presenting cells but interacts directly with the invariant region of the class II MHC molecule

What is a superantigen?
500

Scores less than less value are predictive of an 85% 6-month survival in alcoholic hepatitis unresponsive to steroids.

What is < 0.45?

500

This condition, which can be associated with systemic sclerosis, is characterized by these endoscopic findings.

What is gastric antral vascular ectasia [GAVE]?

500

This activity management technique, characterized by daily modulation of activity based on fatigue/pain, has been adopted for Long COVID patients from ME/CFS and fibromyalgia literature.

What is pacing?

500

The test shown below, when coupled with other special tests, can have sensitivity/specificity over 90% when diagnosing this type of lesion. 

 

What is a SLAP tear?

500

The Contact Allergen of the Year for 2023, this complex molecule is paradoxically found in some emollients used for patients with atopic dermatitis.

What is lanolin?