Drug References
Type of resource that summarizes or interprets original works
What is tertiary literature/resource?
The number of patients needed to receive treatment for one patient to experience a desired outcome
What is number needed to treat (NNT)?
The number of patients who must receive a particular treatment for 1 additional patient to experience a particular adverse outcome
What is number needed to harm (NNH)?
Best quality of evidence based on hierarchy of evidence pyramid
What are systematic reviews and meta-analyses (of RCTs)?
The most common MUE methodology
What is FOCUS-PDCA?
Established inpatient blood glucose goals as 140-180 mg/dL
What is NICE-SUGAR?
Probability that a particular statistical measure of an assumed probability distribution will be greater than or equal to (or less than or equal to in some instances) observed results
What is a p-value?
Risk of an individual having an event given that the patient has not had an event up to a specific point in time
What is a hazard ratio?
Minimum set of recommendations for preparing reports of randomized controlled trials
What is consolidated standards of reporting trials (CONSORT)?
This type of study focuses on analyzing a process at an institution and implementing incremental institutional changes based on the results of the study
What is an MUE?
Established norepinephrine as a first line recommended vasopressor in shock
What is the SOAP II trial?
Incorrect rejection of a true null hypothesis
What is a type I error/false positive?
Failure to reject a null hypothesis that is false
What is a type II error/false negative?
The extent to which you can generalize the findings of a study to other situations, people, settings and measures
What is external validity?
This type of guideline hones in on new literature for select portions of previously defined recommendations
What is a focused update?
A detailed written set of instructions to guide the care of a patient or to assist the practitioner in the performance of a procedure
What is a protocol?
Percentage of patients spared the adverse outcome compared to the control
Measure of association that quantifies ratio of incidence
What is relative risk?
Method used for estimating survival functions from a sample/summarizes the probability of survival over time estimated from a sample
What is a Kaplan-Meier curve?
Methicillin Susceptible Staphlycoccus Aureus and Streptococcus species
What are the most common bugs in endocarditis?
Large curated database of drug information focused primarily on systematic reviews and meta-analyses
What is the Cochrane Library?
Measure of association between exposure and an outcome for retrospective studies
What is odds ratio?
Difference in event rates between two groups, expressed as a proportion of the event rate in the untreated group
What is relative risk reduction?
Quantitative method for determining heterogeneity of studies included in a systematic review or meta-analysis
What is the I2 value?
*DAILY DOUBLE*: This organization is responsible for publishing HIV guidelines
Who is the NIH?