What is an indication for surgical management of ectopic pregnancy?
100
Methotrexate
What is the most frequently used medication to manage ectopic pregnancy?
100
Tubal size less than 3-4cm with no fetal cardiac activity
What is one of the criteria for MTX use?
100
Aspirin and NSAIDS
What are some drugs that can interfere with MTX excretion?
200
Laproscopic procedure
What is a standard surgical approach to ectopic pregnancy?
200
1/3
What is the proportion of ectopic pregnancy cases who are candidates for medical management?
200
Renal impairment
What is a contraindication to MTX use in medical management of ectopic pregnancy?
300
Laparotomy
What is a surgical approach indicated for patients with acute internal bleeding due to ectopic pregnancy?
300
2/3
What is the proportion of ectopic pregnancy cases not candidate for medical management requiring surgical intervention or expressed preference for surgical management?
300
Temperature of 103F, BP of 80/60, HR 130
What are some contraindication to MTX use in the medical management of ectopic pregnancy?
300
serum hCG level
What marker is used to monitor MTX efficacy in the medical management of ectopic pregnancy?
400
Shorter operation time, less perioperative blood loss, less invasive, shorter hospital stay, and lower cost.
What are some advantages for laparoscopic surgery?
400
Prostaglandins, Hyperosmolar glucose, KCL, and Mifeprostone
What are some additional agents used in the medical management of ectopic pregnancy?
400
Dihydrofolate Reductase
What is the enzyme that is responsible for converting DHF to THF critical for dUMP to dTMP conversion? Which enzyme is inhibited by MTX?
400
hCG > 5000 mIU/mL
What is the established threshold for MTX effiacy in the medical management of ectopic pregnancy?
500
The process involving making an incision in the fallopian tube and remove the ectopic gestation
What is salpingostomy?
500
Breastfeeding
What is another contraindication to methotrexate use?
500
Leucovorin (5-formyltetrahydrofolate)
What is an antidote to Methotrexate toxicity? What is a drug that can reduce the efficacy of Methotrexate when coadministered at the same time?
500
Mucositis
What is a side effect seen in patients given MTX and other chemotherapeutic agents?