Alcohol
Opioids
Benzodiazepines
Amphetamines
Nicotine
100

This organ is primarily responsible for metabolizing alcohol in the body

What is the liver?

100

One of the most common physical symptoms of opioid withdrawal, this condition involves excessive sweating, chills, and goosebumps

What is "cold sweats" or "chills"?

100

One of the most common side effects of benzodiazepine use, this symptom causes drowsiness, impaired motor coordination, and sluggish reflexes

What is sedation or drowsiness?

100

Amphetamines increase the release of this neurotransmitter in the brain, which is associated with alertness, mood, and energy levels.

What is dopamine?

100

When nicotine enters the body, it stimulates this organ, causing an increase in heart rate and blood pressure

What is the heart?

200

Excessive alcohol consumption can lead to this liver disease, characterized by the accumulation of fat in liver cells

What is fatty liver disease?

200

Opioid abuse is a leading cause of this life-threatening condition, marked by slow or irregular breathing, which can be fatal without intervention.

What is respiratory depression?

200

During benzodiazepine withdrawal, this psychological symptom can manifest as an inability to concentrate or focus, leading to mental fog and confusion

What is cognitive impairment or "brain fog"?

200

Amphetamines are often abused for their stimulant effects, leading to this psychological state, where a person experiences excessive energy, euphoria, and decreased appetite

What is a stimulant high or euphoria?

200

Nicotine is a major risk factor for this condition, which causes the airways to become narrowed and inflamed, leading to difficulty breathing

What is chronic obstructive pulmonary disease (COPD)?

300

Chronic excessive drinking can lead to this serious liver disease, characterized by scarring and loss of liver function

What is liver cirrhosis?

300

Opioid overdose can be treated with this medication, which reverses the effects of opioids, particularly respiratory depression

What is naloxone (Narcan)?

300

Benzodiazepine withdrawal often causes this symptom, which involves an intense and uncontrollable urge to move, especially in the legs

What is restless leg syndrome?

300

Chronic abuse of amphetamines can lead to this mental health disorder, characterized by paranoia, hallucinations, and intense anxiety

What is amphetamine psychosis?

300

One of the long-term effects of nicotine use, this condition is often caused by prolonged smoking, leading to damage to the lungs and an increased risk of cancer

What is lung cancer?

400

This condition, characterized by a loss of coordination and balance, is a common effect of intoxication by alcohol

What is Ataxia?

400

Long-term opioid use can lead to a reduction in the brain’s production of this neurotransmitter, which is responsible for regulating mood, pleasure, and pain

What is dopamine?

400

This phenomenon, often seen after long-term benzodiazepine use, can cause symptoms like confusion, hallucinations, and agitation, particularly in elderly patients.

What is delirium? 

400

This is one of the most noticeable long-term effects of methamphetamine use on appearance, involving severe dental decay and gum disease

What is "meth mouth"?

400

Smoking nicotine is a major contributor to this disease, which occurs when plaque builds up in the arteries, restricting blood flow and increasing the risk of heart attack and stroke

What is atherosclerosis?

500

Long-term abuse of this drug can result in brain shrinkage, particularly in areas involved with

What is memory and learning?

500

Opioid use can lead to this potentially severe complication in the digestive system, causing constipation that may become chronic and difficult to treat

What is opioid-induced constipation?

500

One of the hallmark symptoms of benzodiazepine withdrawal, this condition causes rapid heartbeat, high blood pressure, and extreme anxiety

What is tachycardia?

500

This condition, caused by the overstimulation of the central nervous system, is a serious side effect of high-dose amphetamine abuse, marked by fever, confusion, and organ failure

What is hyperthermia or heat stroke?

500

Nicotine and other chemicals in cigarettes can damage this part of the body, leading to an increased risk of throat and mouth cancers

What is the larynx or oral cavity?