Not yet a fetus
embryogenesis
Teratogen-tastic
100

This term refers to the three components: embryoblast, fluid-filled cavity, and outer cell layer.

What is a... blastocyst

100

Conservatively by week 20 of fetal development, this is functional

What is....
rudimental hearing

100

any agent or factor that causes malformation of an embryo, as well as can also increase the risk for miscarriage, preterm labor, or stillbirth. 


What is a...

teratogens

200

The membrane lying of the middle ear, Eustachian tube, liver, and pancreas, all develop from this disk germ layer.

What is a... Endoderm

200

By the 4th month these structures ossify, but only by  the 8th month they are free of mesenchyme

What is the...

 malleus, incus and stapes

200

Minor congenital anomalies or functional deficits to the auditory system and CNS are more likely to occur during this period of development 

The fetal stage or weeks 10-20 (ear) weeks 20-40 (CNS

300

Theses external coverings are referred to as _______ and develop from _______________

Branchial Grooves  (develop from ectoderm)

300

Connective tissue around the tympanic membrane begins to harden and form bone, at approximately 

What is...

 Week 12

300

Many women share stories of their last night out [drinking] before they knew they were pregnant, ....this is why their babies don’t have Fetal alcohol syndrome

What is... 

prior to week 3 of development, the pre-embryonic is not susceptible to teratogens

400

What three critical events in the development of auditory structures all begin in week 4?

What are: 

•Branchia arches develop and swell  --> OE
•Otic pit invagination (sink into mesoderm) --> IE
•Stereo acoustic ganglia apparent --> CN VIII

400

The stapes [most likley] developed from which develops from the __________ arch

What is....

2nd Branchial (pharyngeal) arch or Hyoid arch

400

This is a typical configuration of Mondini malformation.

What is...

Unilateral profound Seneorneural hearing loss

500

E represented the cochlear duct at week 8, but which weak is the duct completed coiling?

What is...

•Week 9 (according to Dr. Weaver)

500

Describe the process by which the tympanic membrane forms:

What is...

"the ectodermal epithelial lining at the bottom of the auditory meatus, the endodermal epithelial lining of the tympanic cavity, and an intermediate layer of connective tissue that forms the fibrous stratum.

500

Which cochlear malformation is most likely to occur at ~4th week

What is...
Common cavity

600

Formation of the three semicircular canals occurs around...

What is...
Week 6

600

The greatest period of [percent] change in the cerebrum weight occurs.... 

What/ when is...

Birth -3 years of age

600

When these defects are present: 

1) aural atresia,
2) microtia,
3) ossicular (ear, face, palate) deformities  

with normal inner ear a clinician should suspect this syndrome?

What is...

1st Arch Syndrome

700

Explain the process of gastrulation.

Being in at week 3, gestation, the bilaminar blastocyst structure tri-furcates into three germ layers. The Ectoderm (neural crest gives rise to CNS & PNS); mesoderm (bone and tissue --> middle ear), and Endoderm (gives rise to tissue lining and organs including the middle ear cavity).

700

While many aspects of the auditory system are mature at birth. The following will not be adult-like until someone provide 5 structures that are not adult-like until after birth

Daily Double
What is...

~3 months =Tympanic membrane
~5 months = CN VIII
~6 years = Midbrain (CANS)
~7 years = EAM, and  ET
~8 years = Pons (CANS)
~9 year   = Pinna,
~5 to 20 Years =cerebbelum

700

This congenital anomaly can act as a "port of entry" to the fluid that surrounds the brain and spinal cord (cerebrospinal fluid, or CSF). Sometimes, individuals are not diagnosed with Mondini dysplasia before several episodes of what occurs.

What is...
recurrent meningitis