Neurotransmitters
This is where ~90% of the body's serotonin is produced.
What is the GI tract? (Enterochromaffin cells)
Your patient has had incessant hiccups for the last 24 hours that are refractory to even the scariest of scary movies. You decide to prescribe them this medication to rid them of their ailment.
What is prochlorperazine?
This is the most common ROA for scopolamine.
What is a transdermal patch applied behind the ear?
This is the receptor that meclizine blocks.
What is the H1 receptor?
After their surgery, you prescribe this to your patient to treat their new nausea and vomiting.
What is scopolamine?
This drug class works by blocking a specific neurotransmitter that stimulates both the vomiting center in the brain and acid production in the stomach.
What are antihistamines?
This is the aspect of the vomiting pathway that norepinephrine acts on.
What is nothing? (sorry)
In addition to "regular" nausea and vomiting, anticholinergics are also used to treat this specific sensation.
What is motion sickness?
Substance P is involved in transmission of nauseating stimuli in addition to this sensation.
What is pain?
This is the neurotransmitter and mode of action (agonist/antagonist) that prochlorperazine affects.
What is a dopamine antagonist?
A 67yom patient with a history of DMII, HTN, obesity, ESRD, and kidney transplantation presents to your clinic. They are complaining of fever and new-onset pruritis at a nevus 7mm in diameter on their left forearm. Vitals are as follows: BP 88/56, HR 101, T 38.6ºC, RR 22. On physical exam, you note erythema and scabbing around the lesion as well as lymphangitis of the lymph vessels running down their arm towards the lesion. Lactate is elevated.
You decide to refer the patient to dermatology to rule out melanoma. You also anticipate chemotherapy is in your patient's future, and this is the medication you would prescribe to to treat their chemotherapy-induced nausea and vomiting.
What is granisetron or palonosetron?
Your patient who takes triazolam nightly for insomnia is complaining of allergy symptoms and an unremitting nonproductive cough. You should be weary of prescribing this drug to your patient due to its tendency to cross the blood brain barrier & produce sedation by blocking histamine receptors.
What is promethazine?
(Or DPH, meclizine)
These are the neurotransmitters associated with the sensation of dizziness.
What are acetylcholine and histamine?
Although ondansetron is not approved for this purpose, you may treat a patient with it off-label.
What is gastroenteritis?
This drug class can treat vestibular nausea by blocking transmission in the inner ear labyrinth.
What are anticholinergics?