Indications & Usage
Dosage
Warnings
Efficacy
Eloquent 3 Trial
100

Empliciti with pomalimide and ______ for the treatment of adult patients with multiple myeloma

What is dexamethasone?

100

What dose strengths for Empliciti?

What is 10 and 20?

100

What are the most common adverse reactions (20% or higher) with Empliciti pus Len and dex?

What is diarrhea, pyrexia, and constipation?


100

What is the ORR for Empliciti in combination with pom & dex vs pom & dex alone?

What is 53.3% vs 26.3%?

100

A total of how many patients were included in the study of Empliciti in combo with pom and dex (Eloquent-3)?

What is 117?

200

Patients must have received ______ prior therapies.

What is 2?

200

How is Empliciti administered (IV or Oral)?

What is IV?

200

What are the contradictions for Empliciti?

What are no contraindications?
200

After a minimum follow-up of 9.1 months, Empliciti in combo with pom & dex vs pom & dex alone had a hazard ratio for progression free survival of?

What is .54?

200

What is the median patient age in Eloquent-3?

What is 67 years?

300

Empliciti is a _______f7 directed immunostimylatory antibody.

What is SLAM?

300

What pretreatments must be administered with Empliciti?

What is dexamethasone, H1 blocker, H2 blocker, and acettaminophen?

300

In the Eloquent-2 trial, Grade 3 infusion reactions occurred in ______ of patients?

What is 1%?

300

What is the reduction in the risk of disease progress or death in Eloquent-3?

What is 46%

300

How many patients were refractory to Revlimid in Eloquent-3?

What is 87%

400

What are the therapies a person must have received?

What is Lenalidomide and a protostome inhibitor?


400

What is the recommended dosage of Empliciti in conjunction with pom and low dose dex?

What is 10 mg/kg administered iv every week for the first 2 cycles (28 day cycle) staring at Kyle 3 928 day cycle) administer Empliciti 20 mg/kg iv every 4 weeks?

400

In the Eloquent-3 trial, all patients who experienced an infusion reaction had them during which treatment cycle?

What is the first cycle?


400

What is the VGPR for Epd vs pd in Eloquent 3?

What is 20% vs 8.8%

400

Eloquent-3 was a phase ____ trial?

What is 2?

500

Empliciti's generic name is?

What is Elotuzumab?


500

For patients >75 years of age, what is the dosing of dex?

What is 8 mg?

500

In the Eloquent-3 trial, the only infusion reaction symptom was ________?

What is Chest Discomfort (2%)?

500

What is the PFS for Epd vs Pd in Eloquent-3?

What is 10.3 months vs 4.7 months?

500

What percentage of patients in Eloquent-3 had high cytogenetic risk factors?

What is 5%?