RAAS-tastic
Adrenaline Rush
Super Man
If It's Broke...
Not That Again!
100

What organ is the protein angiotensinogen made in?

Liver

100

What hormone structural class does epinephine fall into?

AA-Derivative

100

What molecule is both testosterone and vitamin D derived from?

Cholesterol

100

What is a tumor of the adrenal gland medulla cells called?

Pheochromocytoma

100

What can cause endemic goiter is isolated inland communities?

Iodine deficiency

200

What receptor for angiotensin II is located on the adrenal grand zona glomerulosa cells?

AT2

200

What functional group is added to norepinephine in the last step of epinephrine synthesis?

Methyl

200

What structure within the testes are the location of spermatogenesis?

Seminiferous tubules

200

What does MAO stand for in the class of MAO inhibitor "1st generation" high potency anti-depressant medications?

Monoamine oxidase

200

What hormone down-regulates CRH in the hypothalamus?

Cortisol

300

Name the action of the enzyme renin.

Converts angiotensinogen to angiotensin I.

300

What tissue type has beta-3 adrenergic receptors?

Lipid/Adipose/Fat tissue

300

Which cell in the testes secrete testosterone?

Leydig cells

300

What hormone is injected a specific times a day to improve fertility with males with low testosterone?

GnRH

300

What are the three organs involved in vitamin D synthesis?

Skin, Liver, Kidney

400

If blood Na+ is high, will aldosterone increase, decrease, or not change.

Decrease

400
What is the action of epinephrine on the lungs?

Bronchodilation

400

What is the target of the hormone inhibin?

Anterior pituitary

400

What is ONE of the three blood test indicators of Conn's Disease?

Higher pH, Lower K+, Higher Na+

400

What enzyme is upregulated by increased PTH that is the last step in creating active vitamin D?

1-alpha-hydroxylase

500

Name the type of cells that secrete renin.

Juxtaglomerular cells

500

What is converted to what by the enzyme adenylate cyclase in the G-protein coupled receptor signaling cascade?

ATP to cAMP

500

Name three glycoprotein hormones.

TSH, LH, FSH, and/or Inhibin

500

What substrate molecule does the medication Aldomet mimic (as an enzyme inhibitor) to prevent excess epinephrine synthesis in people with adrenal medulla tumors?

DOPA

500

Name two hormones that target the kidney.

PTH, Aldosterone