Adrenal
Pituitary
DM Pharm
DM
Hypogonadism/Pagets
100

This hormone released by the hypothalamus stimulates the anterior pituitary to produce ACTH.

What is CRH (corticotropin‑releasing hormone)?

100

This hormone level, when normal for age, effectively rules out acromegaly.

What is a serum IGF‑1 level?

100

This first‑line biguanide decreases hepatic gluconeogenesis, increases insulin sensitivity, and does not cause hypoglycemia.

What is metformin?

100

This autoimmune process destroys pancreatic beta cells, leading to absolute insulin deficiency.

What is Type 1 Diabetes Mellitus?

100

This chromosome abnormality (XXY) is the most common cause of primary hypogonadism in males.

What is Klinefelter syndrome

200

Fat redistribution in Cushing syndrome produces these two classic findings: a dorsocervical fat pad and a rounded plethoric face.

What are a buffalo hump and moon face?

200

This genetic disorder is the most common cause of disproportionate dwarfism.

What is achondroplasia?

200

This class of diabetes medications lowers blood glucose by inhibiting glucose reabsorption in the proximal renal tubules, leading to glucosuria.

What are SGLT2 inhibitors?

200

This dermatologic finding, often seen on the neck or axilla, is associated with insulin resistance.

What is acanthosis nigricans?

200

This laboratory test is typically elevated in Paget’s disease and reflects increased bone turnover.

What is alkaline phosphatase

300

This anesthetic induction medication can precipitate acute adrenal crisis because it suppresses adrenal function.

What is IV etomidate?

300

A 30-year-old patient described a deepening of his voice and enlargement of his hands and feet- is a classic vignette for this disorder.

What is acromegaly?

300

This class of medications stimulates pancreatic beta cells to release insulin regardless of glucose level, increasing the risk of hypoglycemia.

What are sulfonylureas?

300

This HbA1c value or higher is diagnostic for diabetes mellitus.

What is 6.5%?

300

In this type of hypogonadism, LH and FSH levels are elevated due to gonadal failure.

What is primary (hypergonadotropic) hypogonadism

400

This triad of symptoms—is considered classic for pheochromocytoma.

What is the triad of palpitations, headache, and sweating?

400

This medication is first-line treatment for central diabetes insipidus.

What is desmopressin?

400

For patients with type 2 diabetes and chronic kidney disease, this class of medication is recommended because it slows progression of diabetic nephropathy.

What are SGLT2 inhibitors?

400

new

new

400

Testosterone levels should be measured at this time of day because levels peak during this period

What is early morning around 8–10 AM (must say between 8-10am to earn points)

500

An 8 AM plasma cortisol level below this value is considered diagnostic for adrenal insufficiency.

What is 3 mcg/dL?

500

Compression of the optic chiasm by a pituitary macroadenoma classically produces this visual field defect.

What is bitemporal hemianopsia?

500

According to ADA guidelines, patients with type 2 diabetes and established cardiovascular disease should receive this class of medications due to demonstrated cardiovascular risk reduction.

What are GLP-1 receptor agonists or SGLT2 inhibitors?

500

A 22-year-old patient with mild fasting hyperglycemia has a strong family history of diabetes in three generations. The patient is non-obese, has negative autoantibodies, and maintains stable glucose levels without insulin therapy. Genetic testing reveals a positive mutation related to Diabetes.

What is MODY?

500

This rare but serious malignancy is the most common neoplastic complication of Paget’s disease

What is osteosarcoma