OPD Pearls
SO-A-P-I-E
Something Secreting
Adrenal In? More like.... Adrenal Out
Science, Technology, & Society
100

Experiencing a mild case of oral thrush from inhaled corticosteriods, TJ can rinse his mouth with this home remedy solution. 

NaHCO3

100

Upon the inspection of a patient experiencing Cushing you notice this characteristic sign on the back of their neck.

Buffalo hump

100

PTH

Parathyroid Hormone

100

This is the organ where Angiotensinogen arises from

Liver
100

In general, which among these would have the lowest regulations in quality control? Drugs, medical devices, food, or cosmetics?

Cosmetics

200

Frequently using this deep brown disinfectant, you notice that you've developed thyroidal dysfunction 

Iodinated products

200

Looking at the high amount of TSH, but low amounts of T4, you can say that the patient is experiencing this (high or low) activity of the thyroid.

Hypothyroidism

200

Thymosin

Thymus

200

For short-term stress name one catecholamine that is involved in fight, flight, or fright responses 

Adrenaline, Noradrenaline

200

This natural substance from the Berberis vulgaris demonstrate some evidence to be "nature's Ozempic" 

Berberine

300

The usual indication for topical corticosteroids

Pruritis, Atopic dermatitis

300
When planning for the use of anti-thyroid medications, which between the two is considered with a higher risk for agranulocytosis?

PTU

300

GH

Anterior pituitary

300

This potassium-sparing diuretic is an ENaC blocker used in the treatment for primary aldosteronism

Amiloride

300

Frederick Banting, Charles Best, and James Collip sold this patent to the University of Toronto for $1

Insulin

400

Spironolactone is the DOC for this 

Hyperaldosteronism (BAH)

400

To prevent iatrogenic Cushing syndrome, we would use this process of gradually reduce the dosage of a medication.

Dose tapering
400

CRH

Hypothalamus

400

True or False: you might not ever need to consult the AACE Diabetic guidelines for hyposecretory adrenal disorders like Addison disease.

FALSE

400

This contraceptive was featured in the news recently for doubling as an anticancer adjuvant

Ulipristal Acetate (UPA)

500

RAAHHH, This is the 2nd A in RAAS

Aldosterone

500

When evaluating therapy of levothyroxine, a low TSH would indicate that you would increase or decrease the dose

decrease

500

Estrogen (Males)

White Adipose Tissue

500
Zona fasciculata? Zona reticularis? This hormone is secreted by the unmentioned layer of the adrenal cortex

Aldosterone

500

Recently, which hormone is the subject of a mandatory testing policy among US service members aged 30 and older?

Testosterone