Hormone Actions
Clinical vignettes
Homeostasis
Pathology
Name the hormone
100

Which hormone in a daily rhythm influences sleep/wake cycles?

melatonin

100

A teenage girl presents with primary amenorrhea, short stature, and a webbed neck

What is Turner syndrome

100
What is more common in the endocrine system: positive feedback or negative feedback?
Negative feedback
100

What condition is caused by excessive GH secretion in childhood?

What is Gigantism?

100

This thyroid hormone is most biologically active at the nuclear receptor level.

What is Triiodothyronine T3?

200

Which two hormones from pituitary gland regulates puberty?

LH and FSH

200

This condition causes early development of secondary sexual characteristics due to early activation of the hypothalamic-pituitary-gonadal axis.

What is central (gonadotropin-dependent) precocious puberty?

200

Which two hormones are produced by the pancreas to regulate blood glucose levels?

Insulin and glucagon

200

This pituitary tumor cause galactorrhea and amenorrhea

What is prolactinoma ? 

200

Decreased production of this hormone is associated with delayed puberty?

What is GnRH?

300
Which hormone promotes uterine contractions and is responsible for milk production in the mammary glands?
oxytocin
300

An 11-year-old girl is brought in for fatigue, poor school performance, and slowed growth. She has a painless, firm goiter on exam. Labs show elevated TSH and low free T4. Anti–thyroid peroxidase antibodies are positive.

What is autoimmune hypothyroidism (Hashimoto's thyroiditis) ?

300
What two categories of hormones does the hypothalamus produce to regulate the secretion of other hormones?
RH (releasing hormones) and IH (inhibiting hormones)
300

A newborn has prolonged jaundice, poor feeding, hypotonia, and a large posterior fontanelle and has an abnormal new born screen. 

What is congenital hypothyroidism? 

300

This hormone is produced in the zona fasciculata and is the main glucocorticoid involved in stress response.

What is cortisol?

400

This adrenal cortex hormone increases sodium reabsorption and potassium excretion in the kidney.

What is Aldosterone ?

400

A 3-year-old has ambiguous genitalia, salt-wasting crisis, and elevated 17-hydroxyprogesterone levels

What is congenital adrenal hyperplasia (21 hydroxylase deficiency )

400
Calcitonin is secreted when blood calcium levels get too high. It opposes the action of which hormone?
Parathyroid hormone
400

This autoimmune condition of thyroid gland is associated with exophthalmos and tachycardia 

What is Graves disease 

400

This pancreatic alpha-cell hormone raises blood glucose by stimulating glycogenolysis and gluconeogenesis in the liver.

What is glucagon?

500

WhThis posterior pituitary hormone increases water reabsorption in the collecting ducts of the kidney.

Anti diuretic hormone / Arginine vasopressin

500

A 6-year-old boy with a history of brain tumor presents with excessive thirst, frequent urination, and new nocturnal enuresis. He appears dehydrated with hypernatremia. Urine is very dilute.

What is arginine vasopressin deficiency?

500

This hypothalamic hormone is released in a pulsatile manner and is essential for normal reproductive endocrine homeostasis by stimulating both LH and FSH secretion from the anterior pituitary.

What is GnRH ?

500

This tumor of the adrenal medulla secretes catecholamines and presents with episodic hypertension, headache, and sweating.

What is Pheochromocytoma

500

This hypothalamic hormone inhibits prolactin secretion from the anterior pituitary.

What is dopamine (prolactin-inhibiting hormone)?