seasons
100
Jake stabs him in the back.
How does Sam die in season 2?
200
Dean going to hell.
What is Sam trying to stop for the entire third season?
300
Lucifer rises.
What is the conclusion of season 4's plot.
400
Because he thinks the demon blood might make him strong enough.
Why does Sam think he might be able to over power Lucifer.
500
When Castiel mentions the Superman and kryptonite thing when he wasn't supposed to be there to hear it.
How does Sam and Dean know that Castiel is working with Crowley.