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Side effects
Drug Interactions
Mechanism of Action
Types of Seizures
Indications
100
Pedal edema, creatine kinase elevation, decrease platelets, blood dyscrasias, and Rash
What are the side effects of Pregabalin?
100
the level of phenobarbital is increased with the addition of these drugs.
What happens to the drug concentration of phenobarbital when you add oxcarbazepine, phenytoin, rufinamide, valproic acid?
100
GABA agonist but does not react at the GABA receptor, alter GABA uptake, or interfere with GABA transaminase.
What is the mechanism of action of Gabapentin?
100
Focal seizures begin in one hemisphere of the brain.
What is the definition of partial seizures?
100
Ethosuximide and valproic acid are the first line agents.
What are the first line agents for absence seizure?
200
acute pancreatitis, acute hepatic failure, alopecia.
What is the side effects of valproic acid?
200
All of these drugs decrease the level of lamictal by increased metabolism?
What is the effect of lamictal level when you add either phenytoin, carbamazepine, primidone, phenobarbital, and Rufinamide?
200
Blocks T-type calcium currents, blocks sodium channels, and increase GABA production.
What is the mechanism of action of Valproic acid?
200
They are paroxysmal non-epileptic episodes resembling epileptic seizures that can be organic or psychogenic.
What is the definition of non-epileptic seizures?
200
These drugs are considered first line agents for Partial seizure (focal seisures)?
What are carbamezapine, lamotrigine, levetiracetam, oxcarbamazapine, topiramate?
300
aplastic anemia and acute hepatic failure
What is the side effects of Felbamate?
300
Carbamazapine level is decreased with the addition of this drug on board by inhibiting epoxide degradation.
What is the mechanism of drug interaction when you add felbamate to Tegretol?
300
Fast sodium channel blocker, enchnces GABA activity, antagonizes AMPA/Kainate activity, and weak carbonic anhydrase inhibitor
What is mechanism of action of topiramate?
300
Seizures that begin in both hemispheres of the brain.
What is the definition of generalized seizure?
300
These agents are used as first agents for refractory monotherapy partial seizures?
What are lamotrigine, oxcarbazepine, topiramate?
400
Nystagmus, ataxia, drowsiness, cognitive impairment
What is the dose related side effects of phenytoin
400
increase or decerase the level of phenytoin.
What happens to the level of phenytoin when you add Phenobarbital?
400
slow sodium channel blocker
What is mechanism of action of Vimpat?
400
Typically, there are 5 phases of this type of seizure.
How many phases of tonic clonic seizures have?
400
This drug is used as first line agent for Juvenile myoclonic epilepsy.
What is valproic acid?
500
This Drug side effects include a delay of 2-8 weeks rash, SIADH, and blood dyscrasias
What are the side effects of carbamezapine, Oxcarbazepine?
500
it decreases total phenytoin level, then may increases total phenytoin.
What is the interactions of valpoic acid when given with phenytoin?
500
Fast sodium channel blocker.
What are the mechanisms of action for Trileptal, Phenytoin, Tegretol, Cerebyx, Banzel?
500
Any seizures that lasts more than 20 minutes or recurrent seizures of sufficient frequency that the patient does not regain consciousness between episodes.
What is the definition of status epilepticus?
500
These drugs are first line agents for atonic seizure and they are also considered first line agents in myoclonic seisure?
what are clonazepam and valproated?