Show:
Transposons
Euk Gene Regulation
Chromatin Remodeling
Types of Mutations
Causes of Mutation & Repair Mechanisms
100
this enzyme is used in simple transposition to move the gene
transposase
100
this regulatory transcription factor binds to an enhancer to up-regulate transcription
activator
100
nucleosomes are composed of DNA and these proteins
histones
100
a mutation when a nitrogen base is replaced with another base
point mutation (base substitution)
100
Depurination involves the removal of these nitrogen bases
purines (guanine or adenine)
200
transposable elements are termed this when they have all the components required for transposition to occur
complete
200
This type of regulation utilizes different exon combinations to create different proteins from a single gene.
alternative splicing
200
transcriptionally inactive chromatin is very highly compacted and consider this
closed conformation or heterochromatin
200
these mutations occur directly in sperm or egg cells
germline mutations
200
these chemical mutagens modify the structure of nitrogen bases, such as changing cytosine to uracil
base modifiers
300
these types of transposable elements must be converted to RNA first, before becoming DNA for insertion into the genome
retroelements
300
a coactivator binds the enhancer and this molecule at the core promoter in order to activate transcription
TFIID
300
this type of gene silencing is associated with genomic imprinting
DNA methylation
300
the deletion or addition of bases from the sequence
frameshift mutation
300
This type of DNA repair requires a template to ensure that the double stranded break is properly repaired.
homology directed repair (HDR)
400
copy number increases often occur during this cellular process
DNA replication
400
This protein inhibits transcription when it binds to RNA polymerase and the repressor protein (at the silencer) in a trans acting regulatory pathway.
mediator
400
transcription activation occurs in chromatin remodeling by the removal of these
histone octomers
400
an amino acid change occurs but does not change the function of the protein
neutral substitution/mutation
400
the formation of thymine cross-links is commonly associated with this type of mutagen (think UV light)
nonionizing radiation
500
these two enzymes are required for retroelements to move
reverse transcriptase and integrase
500
In RNA interference, this protein complex is required for the siRNA or miRNA to bind to the mRNA for degradation or silencing.
RISC
500
the modifications of these on histones alters the level of gene expression
tails (through acetylation or methylation, for example)
500
the type of mutation shown here: UCA --> UGA
nonsense mutation
500
this enzyme repairs thymine dimers by utilizing light
photolyase