THE CELL: Normal and Altered
IMMUNOLOGY
STRESS AND DISEASE/INFLAMMATION AND WOUND HEALING
INFECTION
CANCER AND GENETICS
100

This organic compound facilitates transportation across cell membranes by acting as receptors, transport channels for electrolytes, and enzymes to drive active pumps?

a.  Lipids

b.  Proteins

c.  Carbohydrates

d.  Nucleic acids

B.  Proteins

100
The antibody that protects mucosal barriers

IgA

100

Characterizes the alarm stage of GAS

Activation of the SNS

100

Capacity of a pathogen to cause severe disease

Virulence

100

The most frequently reported symptom of cancer

Fatigue

200

Under anaerobic conditions, what process provides energy for the cell?

a.  glycolysis

b.  oxidative phosphorylation

c.  lactolysis

d.  endocytosis

A. Glycolysis

200

The C3b subcomponent of complement:

a.  opsonizes microbes to facilitate phagocytosis

b.  dilates arterioles

c.  lyses cells

d.  induces rapid degranulation of mast cells

a.  opsonizes microbes to facilitate phagocytosis

200

Product of the cascade that increases vascular permeability and stimulates nerve endings

Bradykinin

200

Type of infection that requires a host.

viral

200

TNM staging of a man with a 3 cm tumor, mobile node involvement, and no metastases.

T: 2, N: 1, M: 0

300

This process influences the movement of fluid across the arterial and capillary membranes out into the interstitial fluid.

a.  Diffusion

b.  Osmotic Pressure

c.  Active Transport

d.  Hydrostatic Pressure

D.  Hydrostatic Pressure

300

These cells function for a longer time than neutrophils and basophils and are also present later in the inflammatory response.  They are involved in the activation of the adaptive immune response.

macrophages

300

Hormone that increases lipogenesis in the face/trunk.

cortisol

300

Manifestations that would lead you to believe the patient has progressed from HIV to AIDS?

Opportunistic Infections/cancers

300



Which are not autosomal recessive?  Select all that apply.

a.   Duchenne muscular dystrophy

b.   Huntington disease                                       

c.   Turner syndrome

d.   Cystic fibrosis  

e.   PKU    


A.  Duchenne muscular dystrophy

B.  Huntington disease

C.  Turner Syndrome

400

This cellular death process is characterized by enzymatic digestion that may leak out of the cell.

Necrosis

400

Antibody is effective against:

a.  extracellular viruses

b.  virus-infected cells

c.  viral protein synthesis

d.  expression of MHC molecules

a.  extracellular viruses

400

Type of immunity that is decreased when the body is under acute stress.

Cellular immunity

400

Delineates the progression of sepsis to septic shock.

Decrease in BP from massive vasodilation and increased vascular permeability

400



Which of the following are hallmarks of cancer? (Select all that apply)

a.   Genomic stability

b.   Inhibiting angiogenesis

c.   Activation of invasion/ metastasis 

d.   Inducing immune destruction

e.   Evading growth suppressors


C. Activation of invasion/metastasis

E.  Evading growth suppressors

500

A family presents to their primary care provider reporting headache, nausea, weakness, tinnitus, and vomiting. Which of the following would be the most likely mechanism of injury causing these symptoms?

a.  Genetic disorder

b.  Free radicals

c.  toxic chemical agents

d.  nutritional imbalance

C.  Toxic chemical agents

500

Rejection of a kidney transplant occurred after 2 weeks because...  (select all that apply)

a.  Type II hypersensitivity

b.  immune response against donor HLA antigens

c.  Type IV hypersensitivity

d.  immune response against recipient HLA antigens

B.  Immune response against donor HLA antigens

C. Type IV hypersensitivity

500



Which of the following are systemic inflammatory responses?  (Select all that apply)

a. Fever

b. Edema

c. Pain

d. Tachycardia

e. Redness


A. Fever & D. Tachycardia

500



Which of the following can become chronic? (Select all that apply)

a. Hepatitis A

b. Hepatitis B

c. Hepatitis C

d. Hepatitis D

e. Hepatitis E



B & C

500

Genetic disorder that presents as defective transport of chloride ions with sodium imbalance and primarily affects the GI and respiratory systems.  



Cystic Fibrosis