Show:
Structure/Location
Synthesis
Actions/Mechanism
Regulation
Diseases
100

How many 6 carbon rings are in a steroid nucleus?

3

100

Which ring of the the steroid skeleton is broken by UVB radiation in Vitamin D synthesis?

B

100

Which cells of the body does T4 target?

Most cells

100

What mineral cannot be absorbed as well if vitamin D is deficient?

Calcium

100

What does the "R" stand for in MRI?

Resonance 

200
What cells make the protein thyroglobulin?
Thyroid follicular cells
200

Name the enzyme in the kidney that catalyzes the last step to create active vitamin D?

1-alpha-hydroxylase

200

Name one effect

 cortisol has on the 
lymph tissue.

Anti-inflammation and Immunosuppresion


200

If there is high ACTH in blood, will cortisol increase, decrease or stay the

same?

Increase


200

What is the term that describes ALL potential causes of hypercortisolism?

Cushing's Syndrome

300

What structural class do TRH and CRH fall into?

Peptide

300

What enzyme couples together DIT and MIT to make T3?

Thyroid peroxidase

300

What layer of which organ does ACTH act on?

Zona fasiculata

300

If blood calcium is high, does PTH increase, decrease, or stay the same?

Decrease

300

What auto-immune disease leads to antibodies against some of the enzymes/proteins the are part of building T3/T4?

Hashimoto's thyroiditis

400

Calcitonin 

puts calcium back into bone when blood calcium in high. What organ is this secreted from?


Thyroid


400

In what structural location are full

T4 molecules assembled constructed in thyroid tissue?


Colloid

400

Name an organ that PTH targets.

Kidney and bone

400

If cortisol decrease in blood plasma, will ACTH increase, decrease, or stay the same?

Increase

400
What is the disorder leading to weak bones 
called in adults with vitamin D deficiency when the bone mineral ratio is reduced (due to reduced calcium absorption) even though the bone matrix mass remains unchanged?

Osteomalacia

500

What type of bond forms between the two aromatic rings in T4?

Ether bond

500

What transporter creates an energy gradient that powers the Na+I- symport to be able to transport I- into follicular cells?

Na+K+ ATPase

500

Name the effect cortisol has in the body that causes 



hyperglycemia if someone has hypercorticsolism.

Gluconeogenesis

500

If someone has high T4, high TSH, and high TRH and has a tumor, where is the tumor most likely located?

The hypothalamus

500

The three main components of a radioimmunoassay are 1) the radio-labeled antigen, 2) the antigen from plasma, and 3) _______________. 

An 

antibody to that antigen.