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Pathways
Antioxidants
Cancer
Plants and Cancer
Exotic Abortifacients
100

The carotenoids and Xanthophylls can be produced from geranyl-geranyl PP. 

True or False 

True

100

What is the difference between endogenous and exogenous free radicals? and give examples

Endogeneous: from within the body. exampmples include inflammation, stress, infection, cancer, aging. 

Exogenous: from the external environment. examples include pollution, ciggterrs, alchole, heavy metals. 

100

what are the cancer cells that travel through the blood stream to other locations in the body called?

Metastasis

100

What are the different effects of the CYP enzyme? 

Increases: the drug breaks down quicker

Decreases: the drug staysin the body longer

100

Why were europene women told not to travel to war climates?

Their babies will resemble the natives. 

200

The shikimate pathway produces what three amino acids?

Tyrosine, tryptophan, and Phenylalanine

200

which of the following can lead to free radical formation? 

a) Cancer

b) cigarettes

c) Inflammation 

d) all of the above 

200

what type of nucleus do cancerous cells typically have?

Very large nucleus. 

200

What does sulforphane do in cancer cells? 

It inhibits histone deacetylases

200

Were theses people for or aganist abortifacients? 

Female Slaves

Native American women

Slave owners

Physicians

For

For

Aganist

Aganist

300

What is the product of the Mevalonant Pathway?

Geranyl -Geranyl Diphosphate

300

where do free radicals most likely form? 

Mitochondria

300

What are two things that normal cells follow that cancer cells do not follow? 

1. Anchorage dependance 

2. Density dependent Inhibition

300

Chemotherapy drugs from Taxus spp. Works by inhibiting? 

  1. Microtubule depolymerization 

  2. Microtubule polymerization 

  3. Topoisomerase I 

  4. Topoisomerase II

Microtubule depolymerization

300

Why was the knowladge of herbal abortifacients not promoted in Europe? 

the doctors didnt introduce it to the public and the women did not collect any information regarding the topic from the natives. 

400

Name one thing that can be produced from Tyrosine

Dopa, betalains, tyramine, tocopherols


400

What are antioxidents? and how do they help with free radicals?

Pigment molecules that help fight agansit free radicles. Antioxidents donate one of their free electrons to free radicals to make they stable. 

400

The formation of new blood vessels is called?

Angiogenesis

400

What is pharmacokinetics?

The absorption, distribution, metabolism, and excretion of a drug

400

What is the role of BAX 

Apoptois 

500

What are the two starting compound of the shikimate pathway and can it be produced from sucrose? 

Starting materials: PEP & E4P

Yes, it can be made from sucrose

500

What is oxidative stress and why is it harmful? 

An excessive amount of free radicles that damage the macromolecule of our cells. 

500

What are the different treatments for cancer? 

Chemotherapy, Radiation, immunotherapy, surgical removal. 

500

Watch the chemotherapy drugs with which phase of the cell cycle they disrupt. 

  1. Teniposide and etoposide             

  2. Pacitaxel and decetaxel                      

  3. Vincristine and Vinblastine                    

  4. Camptothecin and Topotecan 

1. s-phase

2. M-phase

3. M-pahse

4. s-phase


500

How do growth factors promote cell division?

Bind to the receptos on the plasm membrane to send signals that promote cell division.