CHAPTER FIVE
Excess catecholamines are released through.....
Reuptake
What condition was MDMA originally created to treat?
STOP BLEEDING
What are the two precursors forming acetylcholine
CHOLINE AND ACETYL COENZYME A
What is the functional role of Glutamate?
SYNAPTIC PLASTICITY
Which drugs can bypass the requirement for cellular excitation and cause a release of catecholamines independently of nerve cell firing?
AMPHETAMINE OR METHAMPHETAMINE
The main action of MDMA is to
ENHANCE SEROTONIN RELEASE
What does the drug Vesamicol do?
DECREASES THE RELEASE OF ACETYLCHOLINE FROM THE NERVE TERMINAL
The most effective drug treatment for brief anxiety
BENZODIAZIPINES
Which of the following is not a catecholamine?
GLUTAMINE
Where are the cells found that produce serotonin in the CNS?
RAPHE NUCLEI
What is the potential side effect of Cogentin and Artane when used for Parkinson's disease?
BLOCKS CHOLINERGIC RECEPTORS
Abnormal firing of striatal GABA neurons is seen with what disease?
PARKINSON'S DISEASE
Once synthesis has occurred, a protein called the _______ is responsible for packaging molecules of dopamine into membrane packets for release.
VESICULAR MONOAMINE TRANSPORTER
For what disorder is MDMA shown to provide improvement
PTSD
What is Apoptosis?
PROGRAMMED CELL DEATH
Metabotropic glutamate receptor drugs are of interest and are being developed for what disorders?
DEPRESSION, ANXIETY, COGNITIVE DEFICITS
What drug exerts its pharmacological effects by blocking monoamine reuptake?
COCAINE
Serotonin is synthesized by what amino acid?
TRYPTOPHAN
What category of insecticides cause an almost irreversible inhibition of Acetylcholenesterase (AChE)
ORGANOPHOSPHOROUS COMPOUNDS