Brain Circuits
SSRIs & Anxiety
Panic Disorder
PTSD
Med Safety
100

This circuit is responsible for pathological worry.

What is the CSTC circuit?


100

SSRIs may initially cause this before improvement.

What is temporary worsening of anxiety?

100

Minimum number of symptoms required for a panic attack.

4 symptoms

100

Medication used for PTSD nightmares

prazosin

100

Pregabalin reduces anxiety by decreasing this neurotransmitter

glutamate

200

This brain structure is involved in fear processing.

What is the amygdala?

200

SSRIs typically take this long to show full benefit.

What is 4–6 weeks?

200

Panic attacks peak within this time frame.

minutes

200

Medication class to avoid in PTSD.

benzodiazepines

200

Best performance anxiety treatment before public speaking

propranolol

300

This axis mediates the stress hormone response.

What is the HPA axis?

300

Best response when anxiety worsens after 5 days on sertraline.

What is reassure and continue?

300

Chest pain alone qualifies as a panic attack

false

300

One FDA-approved SSRI for PTSD

sertraline

300

Avoid benzodiazepines in patients with this respiratory condition

COPD

400

This brain area is associated with norepinephrine and arousal.

What is the locus coeruleus?

400

First-line medication class for panic disorder

SSRI

400

This medication class should NOT be used alone long-term

benzodiazepines

400

This symptom cluster includes nightmares and flashbacks.

re-experiencing

400

Combining benzodiazepines and alcohol increases risk of this.

respiratory depression

500

CSTC stands for this four-part loop

Cortico-Striato-Thalamo-Cortical circuit?

500

This SNRI is also used for anxiety disorders.

venlafaxine

500

First-line long-term treatment for panic disorder.

SSRI

500

This alpha-1 blocker reduces trauma-related dreams

prazosin

500

OCD diagnosis requires symptoms lasting at least this long daily.

1 hour per day