Immunoglobulins (Ig)
What Ig is able to cross the placenta?
IgG
Mediated by IgE antibodies and Mast cells
Type I
Virus that causes oral or genital herpes
Herpes Simplex Virus (HSV)
Type of infection caused by normally non-pathogenic microbes
Opportunistic infection (OI)
Biologically inactive compound that must be chemically converted into an active pharmacological form
Prodrug
What Ig is present in breast milk?
IgA
Takes 24–72 hours for sensitized T cells to reach the site and release cytokines that recruit macrophages
Type IV
What type of OI is Histoplasmosis & Cryptococcosis?
Fungal
Final stage of HIV infection
Acquired Immunodeficiency Syndrome (AIDS)
What medication is prescribed to treat oral candidiasis (yeast)?
Nystatin
High levels indicate specifically helminth infections
IgE
Epinephrine would be administered in which type of hypersensitivity (i.e. anaphylaxis)?
Type I
Protection of unvaccinated individuals in the presence of a largely populated area of vaccinated individuals
Herd Immunity
Morphology of the COVID-19 virus
Spherical
Valacyclovir is a prodrug of acyclovir that has been modified with what amino acid?
L-valine ester
High levels of this Ig indicate a current acute infection
IgM
Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE) and Glomerulonephritis
Type III
Measles, mumps, rubella (MMR) is what type of vaccine?
Live (attenuated)
Type of virus that infects bacteria
Bacteriophage
Tamiflu (oseltamivir) is FDA approved for what age?
> 2 weeks
What type of cell produces Igs?
Plasma B-cells
Which hypersensitivity has no antibody involvement?
Type IV
Polio, Rabies & West Nile all affect which organ system?
Neurology/Neurotrophic (Brain)
Norovirus, Rotavirus & Hepatitis A all affect which organ system?
Enteric (GI)
Tamiflu (oseltamivir) inhibits which enzyme?
Neuramindase