Show:
Action Potentials
Membrane Potential
Gates
Potassium
Miscellaneous
100
The time of an action potential
What is 2 msec
100
The ability of membrane to select which ions or small particles can move through freely while restricting passage of others
What is selective permeability
100
These gates make up the voltage gate sodium channel
What is H (inactivation) and M (activation) gates
100
Potassium is know as the _______ channel
What is leaky
100
What does Nernst Equation and what does Goldman equation calculate
What is individual ion potential for Nernst and membrane potential for Goldman
200
Region of neuronal membrane where action potential normally initiated
What is spike-initiation zone
200
Two forces that determine the driving force for membrane potential
What is concentration gradient and electric gradient
200
What is the only gate open at resting membrane potential
What is the H gate
200
The number and direction of potassium being pumped by the Na/K ATPase pump
What is 2 K+ in (3 Na out)
200
This toxin closes sodium channels and is found in puffer fish
What is TTX
300
Information Coding
What is action potential firing frequency
300
Why is the membrane not at equilibrium?
What is to ensure an unbalance of concentration and charges to fire action potentials
300
True or False: the M gate is the only gate to open at depolarization
What is false. The N gate slowly opens
300
The chemical that a doctor injected into a patient to cause the heart to stop beating
What is KCl
300
Two ways to increase the propagation speed of an action potential down and axon. (include resistance)
What is increase internal diameter of axon, which decreases the internal resistance to ion flow. And, wrap axon in myelin, which increases the resistance of plasma membrane to charge flow
400
Describe all 5 phases of an action potential
What is resting potential, rising phase, overshoot, falling phase, undershoot
400
Percent of ATP used by the brain by the Na/K ATPase pump
What is 70%
400
The reason for hyperpolarization
What is the N gate being slow to close, causing excess K+ to leak out, causing the membrane to be more negative
400
This toxin blocks potassium channels
What is TAE
400
This channel provide prolonged hyperpolarization in cardiac action potential
What is calcium gated potassium channel
500
The six characteristics of an action potential
What is Depolarization (less negative membrane potential), Threshold depolarization to fire AP (10-20 mV), All or None, No change in size (propagates without decrement along axon), Reverse polarity, and Refractory period.
500
Describe the lipid bilayer and what type of molecules can/cannot cross
What is lipid bilayer is non polar and doesn't allow polar molecules to cross but allows non polar molecules to cross
500
S4 segment senses the electric field across the membrane and has positively charged ....
What is arginine and lysine
500
This channel is the K+ channel which sets the Vm to -65 mV is open at rest
What is Inward rectifiers K+
500
Ion Conc. Outside Conc. Inside K+ 5 200 Na+ 150 15 Cl- 175 13 Ca2+ 2 .002 What is ion potential for all ions listed
What is K= 98.59 mV Na= 61.54 mV Cl= -69.48 mV Ca= 92.31 mV