Exam 5 Jeopardy!!

Gene Expression

100

1. Which hormone plays a key role in satellite cell activation?

   1. Testosterone

   2. Estrogen

   3. Insulin

   4. IGF1

4. IGF1

200

Which key player acts as a double agent, meaning it serves as both a nuclear and mitochondrial transcription factor

1. AMPK

2. p53

3. CAMKII

4. PGC1alpha

2. p53

300

Which fuel source is predominant at rest?

Lipids

400

Which of the following is not apart of the activation of PGC1-alpha

1. AMPK

2. p53

3. IGF-1

4. CAMKII

3. IGF-1

500

1. Which of the following is the master regulator of muscle mitochondrial content?

   1. TFM

   2. PGC1alpha

   3. NRF

   4. CAMKII
      
      BONUS: Describe the way that way that satellite cells assist in muscle hypertrophy
      
      
      

2. PGC1alpha

BONUS: fuses with the muscle fiber thus increasing the nuclues content of the cell to increase gene and protein transcription

Integration of Metabolism Part 1-2

100

1. Women will oxidize more ______ during exercise compared to men

   1. Carbohydrates

   2. Lipids

   3. Proteins

Lipids

200

Which hormone promotes lipid utilization

1. Aldosterone

2. testosterone

3. Estradiol

4. Progesterone

5. 
   

3. Estradiol

300

1. Which enzyme is most directly associated with the rapid regeneration of ATP from phosphocreatine in muscle?
   
   

Creatine kinase

400

What molecule, critical for shuttling fatty acids into the mitochondrial matrix for energy production, could be responsible for the decline in fat utilization seen at higher workout intensities?

Carnitine

500

What fuel source contributes to the total energy production as exercise begins to approach two hours. 

BONUS: Describe when carbohydrate intake is necessary and why it is beneficial

plasma fatty acids

BONUS: Long duration exercise, 2+ hours, help spare muscle glycogen, maintain blood glucose

Integration of Metabolism Part 3-4

100

1. Which of the following statements about concurrent training and the interference effect is accurate?

   1. Altering the duration, intensity, or frequency of MICT has no impact on the interference effect

   2. Trained individuals are more likely to experience the interference effect

   3. Running is less likely to interfere with muscle hypertrophy compared to cycling

   4. Performing endurance exercise before resistance exercise is recommended for optimal strength gains

2. Trained individuals are more likely to experience the interference effect

200

• Which type of muscle fiber has a higher concentration of ATP and PCr

  1. Type IIX

  2. Type IIA

  3. Type I

Type I

300

• What kind of muscle fibers are glycolytic, meaning it favors the lactate system

  1. Type 1

  2. Type IIX

  3. Type IIA

2. Type IIX

400

What type of training increases the enzymatic activity of our anaerobic energy systems, specifically in relation to glycoclysis and phosphocreatine breakdown (i.e. creatine kinase, phosphorylase)

Sprint training

500

True/False. Chronic endurance training results in a greater reliance on fats rather than carbohydrates at the same absolute intensity.

BONUS: Name some adaptations to endurance training

True

BONUS: increased mitochondrial content which enhances the capacity for fatty acid oxidation, increased VO2max, increases the lipid:carbs used during prolonged exercise, increased aerobic endurance performance, and cardiorespiratory fitness 

Random

100

Which signaling protein involved in mitochondrial biogenesis is also involved in blocking the muscle hypertrophy pathway.

AMPK

200

What happens to carbohydrate metabolism when exercising at the same relative intensity at altitude 

1. increase

2. decrease

3. stay the same

1. increase

300

What value provides the normal values for a given variable

Reference interval

400

Which energy source is stored in the highest capacity in the body?

Adipose Triacylglycerols

500

As intensity increases, which fuel source is metabolized anaerobically at a greater proportion

BONUS:Describe the change in energy source proportions at different exercise intensities and durations

carbohydrates

BONUS: 

During short-duration, high-intensity exercise, such as interval training, anaerobic energy systems dominate, including the use of stored ATP, phosphocreatine, and rapid glycolysis

During prolonged exercise:

Initially, carbohydrate metabolism is high, utilizing muscle and liver glycogen [our conversation history].

As exercise duration approaches two hours, there is a greater reliance on fat oxidation