Show:
Clinical Features
Heterozygous vs Homozygous
Molecular/Biochemical
Show Me The Numbers
Psycho-social Considerations
100
An excessively high cholesterol levels.
What is hypercolesterolima?
100
This form is more severe
What is homozygous FH?
100
Pathway by which dietary lipids are processed
What is the exogenous pathway? 
100
The amount of FH caused by AD inherited mutations in the LDLR gene.
What is 70%?
100
FH Foundation, National Lipid Association, and Mended Hearts.
What are support groups/client resources?
200
Accumulation of LDL in arterial walls.
What is atherosclerosis?
200
This form has more variability.
What is heterozygous FH?
200
Pathway by which lipids are produced by the body.
What is the endogenous pathway?
200
The prevalence of FH worldwide.
What is 1:250?
200
Feelings resulting from deviations from lifestyles recommendations.
What is guilt/shame?
300
Failure of oxygenated blood to reach heart muscle.
What is a heart attack?
300
This form is dividing into 3 groups of functional receptors.
What is homozygous FH?
300
Areas of the LDL receptor that can be altered by mutations.
What are domains?
300
Percentage of FH individuals likely undiagnosed in the US.
What is 90%?
300
"Better to know, removal of guilt, got nothing new"
What are responses to genetic testing?
400
Yellowish grey rim of the cornea.
What is aarcus cornea?
400
Patients with this form frequently experience myocardial infarctions (MI) before 30.
What is homozygous FH?
400
Cells produce LDL receptors when LDL concentration is at this level.
What is low?
400
Percent contribution of APOB mutations to FH.
What is 2-5%?
400
A feature of FH that might make a person feel uncomfortable about appearance.
What are xanthomas?
500
Cholesterol deposits in the eyelids, elbows, knees, and ankles.
What are xanthomas?
500
This form commonly has xanthelasma, or xanthomas of the eye lids.
What is heterozygous FH?
500
LDLR is the most common gene in FH, but this is the second most common.
What is APOB?
500
Xanthomas and aarcus cornea present before this age a used to diagnose FH.
What is 60?
500
Potential source of fear during FH diagnosis.
What is a chance of early death?