Sickle Cell Disease
Sickle cell originated where and spread worldwide
What is AFRICA
There are more than this many different CF gene mutations known.
what is 1,000
This system in the body, responsible for carrying oxygen, is directly impacted by the sickling of cells.
What is the BLOOD SYSTEM
Cystic fibrosis affects this many genes.
what is ONE
This life-saving procedure replaces a patient’s faulty blood-forming cells and is currently the only curative treatment for sickle cell disease.
What is a STEM CELL TRANSPLANT
In what year did 100,000 Americans reportedly have the disease
What is 2024
This term describes mutation types in CF that produce no functional protein at all.
What is NULL MUTATIONS
People with sickle cell disease often experience these painful episodes during adolescence and adulthood.
What are PAIN CRISES
Mutations in cystic fibrosis can either reduce protein function or do this entirely.
What is PREVENT PROTEIN PRODUCTION
People with sickle cell disease often require these to increase healthy red blood cells during severe anemia or crises.
What are BLOOD TRANSFUSIONS
Sickle cell is a disorder of what
what is HEMOGLOBIN
The main organ that cystic fibrosis affects due to thick, sticky mucus.
what is THE LUNGS
Infants with sickle cell disease are at particular risk for these dangerous bloodstream complications.
What are BLOOD INFECTIONS
Cystic fibrosis is caused by changes in a single one of these.
What is a GENE
Used heavily in cystic fibrosis, these drugs help fight the frequent bacterial lung infections caused by thick mucus.
What are ANTIBIOTICS
Infants with sickle cell can often have blood infections and fevers that can reach up to what
what is 104 DEGREES
Because CF is caused by a single gene defect, it is considered an ideal model for this precise medical technique.
What is GENE EDITING
This organ, along with the lungs and spleen, is commonly affected by sickle cell disease.
What are the KIDNEYS
This life-threatening disorder fills the lungs with thick mucus, leading to chronic infections.
What is CYSTIC FIBROSIS
This future-focused treatment approach is being developed for cystic fibrosis and may one day correct the defective gene.
What is GENE THERAPY