XT/xR
What does the T and R stand for??
What is... T for Tissue (DNA) and R for RNA
What is the difference between xF and xF+?
Which one is better?
What is....difference in number of genes (105 vs 523) sequenced and CT DNA chart with xF+
***xF+ same amount of blood but more information on report
Can the NM/liquid biopsy blood be used for the xG (hereditary) order as well? Or do you need a different kit/blood?
What is...no, you need a different kit. xF/xF+ and NM go to a different lab than xG (hereditary)
What form must you get signed with all blood draws?
What is....the Consent form!
Is Tempus FDA approved?
What is....Yes!!
Tempus xT CDx assay with normal match is FDA approved!
Can RNA (xR) be added on to an order by emailing Mechelle or I?
What is...no
All assays need to have an order placed by you/DR.
**We can add on IHC/Algos to anything you need by email request.
What percentage of pts will have actionable mutations found in a liquid biopsy that was missed by solid tissue alone?
What is...9%
For my breast peeps...this number increases to 20%!!!!
What color if the xG/xG+ kit? What is the TAT?
What is...gold! TAT- 14-21 days AFTER BLOOD RECEIVED
Don't forget consent needed!!
Where is the consent form located?
What is...in the Tempus kit.
Also available online...link is in our email signatures
What needs to be on all blood samples?
what is...pts name, DOB (2 identifiers) and date of collection
Why is adding RNA important to all xT (DNA) orders?
What percentage of actionable mutations are found through RNA alone?
What is...RNA will find certain mutations DNA alone will miss.
The percentage is 29%!!!
Can the blood from the Normal match sample be used for the xF/xF+ (liquid Biopsy)? Same blood or does the pt need another draw?
What is...yes, same blood can be used for NM and xF/xF+! No extra blood needed!
What is the difference between xG, xG+ and xG+ RNA?
what is xG- 40 common cancers
xG+-77 common and rare
xG+ RNA- 77 common and rare and more information with upgrading/downgrading, better support of detection
When can the financial assistance form be submitted for approval?
What is....anytime. before, during or after treatment.
Ideally before so pts know how much they will pay out of pocket
What is CTS ordering? why is this an important way to order?
What is...Comprehensive Therapy Selection...first option in portal to order. This is "future proof" to provide the best results to pts.
What is a Normal Match (NM) sample and why is this needed with a xT CDx/xR order?
What is...a Normal Match sample is a blood sample that is needed with all solid tissue CDx orders (FDA approved). This provides more accurate results and calls out any potential hereditary mutations. This compares the pts DNA to themselves instead of a "reference" sample. 28% reduction in somatic false positive calls
How many tubes of Blood are needed for xF/xF+, what type of tubes and what is the TAT?
What is...2 Streck tubes and TAT: 7-9 days
WOOHOOOO!!!!!!!
DAILY DOUBLE!!!!!!!
What are the 6 hereditary cancers that NCCN recommends to test all pts?
How do you order Mobile Phlebotomy?
What is....drop down on the portal as a "YES"
To add on later, "modify order" on the portal and hit "request mobile phlebotomy"
WOOHOOOO!!!
DAILY DOUBLE!!!!!!!
How many days is "Tempus Blood" good for?
What are the Algorithmic (Algos) Test we offer and do we need addition tissue for testing?
Tempus offers 6 algos (Most need RNA and NM to complete) FYI...Can be added on after report is delivered:
Immune Profile Score (IPS),
Homologous Recombination Deficiency (HRD),
Tumor Origin (TO), DPYD, UGT1A1 and PurISTSM
No additional tissue is required
Using a ctDNA-guided approach (xF+) was associated with a 56% reduction in the risk of disease progression with early _____ gene mutation detection in Breast cancer patients.
What is....ESR1
Does Tempus offer Free genetic counseling?
What is ...Yes! Information will be on the report
We also offer free family testing for any positive results.
What is different when submitting a xG/xG+ order versus a somatic order?
What is...more information needed, a separate form will pop up on the portal that needs to be filled out with family history of cancer. This is very important to fill out with as much information as you can.
How many assays can be ordered on 1 order form/placed in the portal for a patient at the same time?
what is....all of them! We try to make it as easy as possible for you!
Assays: xT/xR, XF/xF+, xG/xG+, MRD