I'm Really Really Fast
Let's Break it Down (STRmix)
Let's Break it Down... Again
Maths
CSI: Contributor Scene Investigation
200

This color coded indicator indicates the DNA profile generated contains quality score flags, which. 

What is a yellow checkmark?

200

This is the pre-check of the data entered into the software and the MCMC process.

What is Burn In?

200

This process proposes genotype combinations and biological parameters to best describe the profile obtained. 

What is deconvolution?

200

STRmix™ is used to calculate this key statistical value in DNA mixture interpretation.

What is a likelihood ratio (LR)?

200

This conclusion is reached when the reference sample is not represented in the evidence sample.

What is excluded?

400

This chemistry, utilized in the Rapid Sample Cartridge's, amplifies 24 short tandem repeats using 6 dye channels. 

What is ACE Globalfiler Express?

400

The initial _________ accepts are discarded during the burn-in phase. (What Number)

The initial 100,000 accepts 

400

An Indication on how peaks paired together throughout the profile. This parameter is optimized in Model Maker

What is Allelic Variance?

400

These population-based values are essential for accurate statistical calculations.

What are allele frequencies?

400

When an evidence profile is too partial or too complex, this conclusion may be reached.

What is unsuitable for comparison?

600

This analysis software is used to visualize the electropherogram for Rapid samples.

What is GeneMarker?

600

The total amount of DNA product after PCR made up by the  genuine allele plus its stutter by product.

What is Total Allelic Product?

600

One or more chains has become stuck in different parts of the probability space is represented by what diagnostic?

What is Gelman - Rubin?

600

Method of calculating an LR distribution which a quantile can then be chosen from in order to report a probability interval (credible interval)

What is Highest Posterior Density?

600
This phenomena is represented by the letter Q

What is dropout?

800

These loci are missing from a sample processed with Rapid (in comparison to Fusion 6C).

What are Penta E and Penta D. 

800

This is developed during the 'profile building stage' of deconvolution and then compared to the observed profile.

What is the expected profile?

800

This principle, incorporated in version 2.6 of STRmix will prevent large peak imbalances at low expected peak heights from being as equally likely as small differences between observed and expected peaks

What is the Taylor Quantum Effect?

800

Abbreviated MHA, this considers whether to step to the proposed state or stay in the current state.

What is Metropolis Hasting Algorithm?

800

This aspect of a DNA profile is manually assessed by the analyst and entered into STRmix. STRmix cannot function without this input. 

What is Number of Contributors?

1000

This letter is used at the beginning of specimen IDs for standards that are entered to CODIS.

What is 'R'?

1000

This diagnostic is a summary of fit of the modeled or expected profile compared with the observed profile. This is averaged across all chains for all iterations of the post burn-in phase of the MCMC.

What is average log(likelihood)?

1000

STRmix uses this type of distribution for drop in

What is a gamma distribution?

1000

This likelihood ratio takes into account relatives in the pool of unknown contributors

What is the Unified LR?

1000

Genotype sets that best explain the observed data are given a numerical value called what

What are weights?