ABORH
Pattern of ABH antigen inheritence.
What is Autosomal Co-Dominant?
Immunoglobulin that is primarily indicated in secondary immune response.
What is IgG?
Amount (in vials) of Rho(D) Immunoglobulin given to Rh Pos mothers.
What is none?
Tests performed on cord blood.
What is ABO (Front only), DAT (IgG). Weak D Bonus (10pts).
Patient has no history and/or no current abnormal results.
What is IS crossmatch?
Blood type with least amount of H antigen.
What is A1B?
Immunoglobulin that is most efficient in binding complement.
What is IgM?
Quantitative measurement of fetal-maternal hemorrhage.
What is Kleihauer-Betke (or KB) stain?
Two reasons a Cord blood might be run.
1. Group O mother
2. Rh Neg mother
3. Hx of AB
4. Doctor request
Patient has history and/or current abnormal results.
What is AHG crossmatch?
Missing or abnormal epitopes on the D Antigen.
What is Partial D?
Two examples of antigens that may demonstrate dosage.
Rh, Kidd, Duffy, MNS
Rhogam provides ____________ immunity against fetal D antigens.
What is "passive"?
Severe case of hyperbillirubinemia resulting from the buildup of excess bilirubin in the brain. Causes seizures, brain damage, and death.
What is Kernicterus?
ABO of FFP that a patient with O blood type can recieve.
Distinguishing factor of Bombay (hh) phenotype patients and regular O (H) phenotype patients.
What is O (H) phenotype patients react with Anti-H and Bombay do not?
A significant difference in antibody reaction strength depending on the quantity of the target antigen present on a target red blood cell.
What is dosage?
Gestational age that antenatal (during pregnancy) Rhogam is given.
What is 28 weeks?
Possible cause of false positive results when testing cord blood without washing it first.
What is Wharton's Jelly?
The cell chosen when performing Positive QC for phenotyping/antigen matching.
The immunodominant sugar molecule in Group A patients.
What is N-acetyl-D-galactosamine (or Galactosamine)
Method of ruling out a clinically significant antibody when performing an extended panel.
Find a cell positive for the antigen being ruled out and negative for all other antigens not ruled out.
Amount of fetal blood in mL that each dose of Rhogam covers.
What is 30 mL?
Severe cause of HDFN that not only causes alloimmune hemolysis, but severe anemia caused by interference of erythropoiesis (RBC production).
What is Anti-K?
Method of ruling out a clinically significant antibody when performing an extended panel.
Find a cell positive for the antigen being ruled out and negative for all other antigens not ruled out.