🫀Take It to Heart
💥 Hormone Havoc
🚑 Code Brown
⚠️ Red Flags
🦠 The Next Pandemic
🕵️♂️Glomerular Mysteries
🌪️Neuro- Inflammation
⚡Hemodynamic Havoc
💉Autoimmune Armory
FINAL JEOPARDY
100
Leg pain at rest and skin ulceration
Critical limb ischemia
100
A hypertensive crisis is triggered by anesthesia in a patient with a known adrenal mass. What is the likely diagnosis?
Pheochromocytoma
100
A 72-year-old with a history of cirrhosis presents with hematemesis and hypotension. What medication should be administered immediately?
Octreotide and IV antibiotics (ceftriaxone)
200
Hypotension, back pain, and drop in hemoglobin level after femoral artery access for cardiac catheterization
Retroperitoneal hemorrhage
200
This endocrine emergency presents with bradycardia, hypotension, hypothermia, hypoglycemia and altered mental status, often triggered by infection
Myxedema coma
200
A patient with alcohol use disorder presents with profound hematemesis and shock. Endoscopy reveals red whale signs and large esophageal varices. What definitive procedure is indicated if bleeding persists despite medical and endoscopic therapy?
Transjugular intrahepatic portosystemic shunt (TIPS)?
300
Concentric ventricular wall thickness with low QRS voltage
Cardiac amyloidosis
300
A 26-year-old with type 1 diabetes presents with polyuria, Kussmaul respirations, and an anion gap metabolic acidosis. Potassium is 3.1 mEq/L. What is the most critical step before starting an insulin drip?
IV potassium replacement to at least >3.3 mEq/L before insulin administration?
300
A patient presents with massive lower GI bleeding. After resuscitation, colonoscopy is inconclusive due to active bleeding. What is the next best step?
CT angiography of the abdomen
400
A 40-year-old male with a history of chronic alcohol use presents with confusion, asterixis, and an elevated INR. His hemoglobin is 8 g/dL, and his platelets are low. What is the diagnosis?
Acute liver failure
400
A 48-year-old woman recently returned from a trip to Southeast Asia. She develops a high fever, jaundice, and dark urine, and her laboratory tests show a positive PCR for Zika virus. What is the primary vector responsible for Zika virus transmission?
Aedes mosquito
400
A 55-year-old female with a history of systemic lupus erythematosus (SLE) presents with worsening edema and elevated serum creatinine. Urinalysis shows 3+ protein and RBCs. What is the likely cause of her kidney involvement?
Lupus nephritis
600
A 35-year-old male presents with fever, abdominal pain, and weight loss. His CBC shows a normocytic anemia with a white blood cell count of 15,000/μL, and a peripheral blood smear reveals tear drop-shaped cells. What is the most likely diagnosis?
Myelofibrosis
600
A 33-year-old male healthcare worker in the United States develops flu-like symptoms after treating a patient with Hantavirus Pulmonary Syndrome (HPS). He recently traveled to the southwestern U.S., where there has been a spike in cases. What is the primary reservoir of Hantavirus?
Rodents (deer mice)
600
A 50-year-old male with a history of hepatitis C presents with renal insufficiency, hematuria, and proteinuria. His urinalysis shows 3+ protein, RBCs, and granular casts. What is the most likely diagnosis?
Membranoproliferative glomerulonephritis (MPGN)
800
A 28-year-old woman presents with severe fatigue, pallor, and new-onset bleeding gums. Her CBC shows pancytopenia with low WBC, hemoglobin, and platelets. A bone marrow biopsy reveals hypercellularity with blasts. What is the next best step in diagnosing this condition?
Flow cytometry
800
A 55-year-old male presents with a rapidly progressive illness characterized by fever, malaise, and severe gastrointestinal symptoms. Laboratory tests reveal a positive PCR for Nipah virus. What is the most likely mode of transmission for this virus?
Bat saliva or urine
800
A 50-year-old male presents with a rapid decline in renal function, hematuria, and proteinuria. His urinalysis shows RBC casts and dysmorphic red blood cells. Renal biopsy reveals crescent formation in multiple glomeruli. What is the most likely diagnosis?
Rapidly progressive glomerulonephritis (RPGN)
1000
A 28-year-old female presents with progressive limb weakness and sensory loss, followed by respiratory distress. CSF analysis shows albuminocytologic dissociation. What is the likely diagnosis?
Guillain-Barré syndrome (GBS)
1000
A 55-year-old male with a history of hypertension presents with hypotension, tachycardia, and cool extremities. His central venous pressure (CVP) is low, and his cardiac output is reduced. What is the most likely diagnosis?
Hypovolemic shock
1000
A 40-year-old male presents with painful muscle weakness, difficulty swallowing, and a heliotrope rash. Which specific antibodies are commonly associated with this condition?
anti-Jo-1 antibodies
1500
A 45-year-old man presents with acute vision loss in one eye, pain on eye movement, and a history of relapsing neurological symptoms. MRI shows a single, large optic nerve lesion, diagnosis of neuromyelitis optica is made. What are the antibodies associated with this condition?
AQP4-IgG
1500
A 60-year-old man with a history of diabetes and renal failure presents in the ICU with hypotension and elevated blood lactate. Despite receiving appropriate volume resuscitation, his condition does not improve. His cardiac output is low, and his systemic vascular resistance is high. What is the most likely diagnosis?
Septic shock
1500
A 35-year-old male presents with recurrent oral and genital ulcers, uveitis, and erythema nodosum. What is the first-line treatment for this condition?
Colchicine and steroids
2000
A 36-year-old female presents with a progressive constellation of symptoms, including fatigue, muscle weakness, and autonomic dysfunction. MRI shows lesions in the brainstem and cerebellum characteristic of anti-MAG neuropathy. What is the characteristic immunological marker?
Anti-myelin-associated glycoprotein (MAG) antibodies
2000
A 50-year-old female with a history of chronic liver disease presents with confusion, hypotension, and ascites. Her cardiac output is within normal limits, but her systemic vascular resistance is low, and her central venous pressure is normal. What is the likely diagnosis?
Hepatorenal syndrome (HRS),
2000
A 70-year-old male with a history of polymyalgia rheumatica (PMR) presents with persistent, localized temporal headaches, scalp tenderness, and visual disturbances. His ESR is markedly elevated, and his temporal artery biopsy shows giant cell infiltration. What is the risk if untreated? (3 answers)
vision loss, aortic aneurysms, and stroke
2000
This U.S. President, born on February 12, 1809, is known for his leadership during the American Civil War and for delivering the Gettysburg Address.
