What is FOP?
How many people does FOP occur in?
It occurs in 1 in 2 million people.
When does the ossification occur?
Happens after minor injuries to soft tissue or sometimes without clear triggers to the muscle.
What are early signs of FOP?
Inward bent toes
Is there a cure for FOP?
Nope
What is the average life span of a person with FOP?
56 years
What does the mutated ACVR1 cause?
An increase in active osteoblasts.
How do you test for FOP?
Genetic testing and Physical exams
What can you take to manage FOP?
Corticosteroids
What type of Disorder is FOP
Genetic Disorder
On what chromosome does the mutated ACVR1 protein come from?
Chromosome 2
What is ONE BIG sign for FOP later in life?
Tumor shaped bumps
Surgery
What is the process that it goes through to ossify the muscle?
Inflammation/Soft Tissue Replacement/Bone Formation
How can you get FOP?
Inherited in an autosomal dominant pattern or due to a new mutation in the ACVR1 gene during early development.