Renal
Immune
Endocrine
Endocrine
Mystery
100

Antidiuretic hormone exerts its effect on this second messenger system.

What is...


cAMP messenger system
100

Monocytes travel from the circulatory system to general connective tissues, where they differentiate into what cell type?

What is...


Macrophages

100

Hormones care made of the following ___________, ________, and _____________.

What are peptides, steroids, amines. 

100

What is the major hormone responsible for mediating the body's general response to stress?

What is cortisol?

100

All of the glomeruli are located in the renal ________

What is...

Cortex

200

Filtration occurs in the _______, most reabsorption occurs in the _________ and urine is transported from the kidney to the bladder in the ________.

What is...

glomerulus, proximal tubule, ureter

200

Cytotoxic T cells require this protein to recognize foreign antigens.

What is...

Class I MHC proteins

200

 True or False: The mechanism of action of lipid-soluble hormones is generally via the stimulation or inhibition of specific DNA-dependent protein synthesis.

What is true. 
200

To synthesize thyroid hormones, iodine is attached to ____________________?

What is the amino acid, 'tyrosine.'

200

The countercurrent exchange system operates because fluid flows in opposite directions through the two segments of the _____________ and the gradient is maintained by the _______________.

What is...


Loop of Henle, Vasa Recta

300

Which of the following would cause the greatest increase in the GFR?

Afferent arteriolar constriction

Efferent arteriolar constriction

Renal artery constriction

Renal vein constriction 

What is...

Efferent arteriolar constriction

300

A drug company produces an anti-venom for snake bites and terms it "snake rescue gamma globulin."  The anti-venom is probably made from which type of antibody? and WHY?

What is...

IgG

300

A patient appears in a clinic complaining of irritability and chronic sweatiness. He also has a lump in his neck near his larynx. Blood tests show he has low levels of thyroid-stimulating hormone (TSH) in his plasma. Which of the following is the most likely diagnosis?

What is Grave's disease

300

In children experiencing significant stress for the longest period of time results in a decreased __________. 

What is bone and mineral density?

300

A 21-year-old woman is stung by a bee. Within 5 minutes she develops severe dyspnea. On her skin are blotchy areas of erythema. She is given an injection of epinephrine and improves over the next 30 minutes. She receives therapy over the next year in which she receives small injections of bee venom. The most likely goal of this therapy is replacement of which of the following forms of immunoglobulin on her mast cells?

What is...


IgE

400

After prolonged exertion in a hot climate, baroreceptors would __________ firing, leading to __________ secretion of __________ and thus __________ renal reabsorption of __________.

What is...


decrease; increased; vasopressin; increased; water

400

Adaptive immune responses differ from innate immune responses in that the adaptive response is mediated by lymphocytes. (T/F)

What is...


True

400

Which of the following is NOT stimulated by cortisol during stress?

Gluconeogenesis

Protein catabolism

Glucose uptake into muscle cells

Triglyceride catabolism in adipose cells

Decreased sensitivity to insulin 

What is "glucose uptake into muscle cells."

400

Which is a result of an absence of thyroid hormones during fetal development?

Acromegaly

Cushing's syndrome

Congenital hypothyroidism (cretinism)

Graves' disease

Addison's disease 

What is 'congenital hypothyroidism (cretinism).'

400

This endocrine hormone stimulates the secretion of cortisol


What is...

Adrenocorticotropic Hormone (ACTH, corticotropin)



500
What composes the Juxtaglomerular Apparatus (2 structures)

What is...

Macula Densa and Juxtaglomerular cells

500

What cell type binds to antigens on plasma membranes of target cells and directly destroys the cells?

What is...

Cytotoxic T cells

500

Which is NOT an effect of parathyroid hormone?

Increases the bone-degrading activity of osteoclasts

Decreases reabsorption of calcium by the kidneys

Promotes vitamin D synthesis, leading to increased intestinal absorption of calcium

Increases plasma [Ca2+]

Decreases reabsorption of phosphate by the kidneys 

What is 'decreases reabsorption of calcium by the kidneys.'

500

Which statement best describes the manner in which growth hormone stimulates cell proliferation?

It directly stimulates cell division in most tissues.

It stimulates the release of insulin-like growth factor I (IGF-1) from the liver and other target tissues of growth hormone.

It stimulates metabolism. 

It stimulates the release of eicosanoids from lymphoid tissues.

It stimulates sleep. 

What is 'stimulates the release of insulin-like growth factor I (IGF-1) from the liver and other target tissues of growth hormone.'

500

Why might different MHC I molecules between donor and recipient cells lead to rejection of a transplanted organ or tissue?

  1. The natural killer cells in the recipient will identify the MHC I molecules on transplanted organ as non-self proteins, causing lysis of transplanted cells. Other host cells will join to phagocytize the foreign cells.
  2. The neutrophils in the recipient will identify the MHC I molecules on transplanted organ as non-self proteins, causing lysis of transplanted cells. Other host cells will join to phagocytize the foreign cells.
  3. B lymphocytes in the recipient will identify the MHC I molecules on transplanted organ as non-self proteins. The foreign cells will then be engulfed and destroyed by B lymphocytes.
  4. The macrophages in the recipient will identify the MHC I molecules on transplanted organ as non-self proteins, causing lysis of transplanted cells. Other host cells will join to phagocytize the foreign cells.