Disease & Epidemiology
Pathogenesis
Innate Immunity
Adaptive Immunity
Where Are We?
100

______ is the number of new cases of a disease in a specific period of time. 

What is Incidence?

100

The ability to cause a disease.

What is Pathogenicity?

100

Chemical messengers that regulate the intensity and duration of the immune response. 

What are Cytokines?

100

Adaptive Immunity depends on these two characteristics. 

What is Specificity and Memory? 

100

Mucociliary Escalator

What is the Respiratory System?

200

A disease acquired by many people in a given geographic region in a short time.

What is an epidemic disease?

200

Stage of pathogenesis that involves attachment to the host cell. 

What is Adhesion? 

200

_______ chemical mediators are produced by microbes that are part of the microbiome. 

What are Exogenous Chemical Mediators?

200

Part of the Adaptive Immune System that targets extracellular pathogens via antibodies. 

What is Humoral Immunity? 

200

Lactobacilli and Lactic Acid

What is the Urogential System?

300

A disease acquired from hospital settings.

What is a nosocomial disease?

300

Toxin released when the cell dies, causing a systemic inflammatory response. 

What is an Endotoxin (Lipid A)? 

300

In inflammation, increased permeability of blood vessels causes ________. 

What is Edema (Swelling)?

300

This type of glycoprotein that is used to display antigens is found only on APCs. 

What is MHC II? 

300

Peyer's Patches

What is the Digestive System?

400

To determine the etiologic agent of a disease, you need to fulfill the criteria from the ______________.

What are the Koch's Postulates?

400

Simultaneous infection of a cell by different strains of a virus results in the mixing of genes. Can lead to pandemics. 

What is Antigenic Shift?

400

Destroys extracellular bacteria by releasing toxic molecules. The first one on the scene of infection. 

What are Neutrophils?

400

The main target of activated Cytotoxic T Cells (Killer Cells) are ________. 

What are Intracellular Pathogens? 

400

Leukocyte Facilitated Mechanism

What is the Nervous System?

500

In which period of disease are the symptoms too general for diagnosis? 

What is the prodromal period?
500

Name a structure that can be used to evade phagocytosis. 

Proteases, Capsules, Biofilms, M protein, Opa protein, or Mycolic Acid

500

Name an outcome of complement activation. 

Cytolysis, Inflammation, Chemotaxis, and Opsonization

500

Name an outcome of antigen-antibody.

Agglutination, Opsonization, ADCC, Neutralization, and Activation of the Complement System.

500

Mucin is responsible for holding a film to this specific structure. 

What are the Eyes?