Da Gut
The majority of microbes in your gut are symbiotic, or in other words are
What is Mutualistic?
This cranial nerve directly connects the gut and brain
What is the Vagus (CN X)?
This refers to the years we remain healthy and free from disease.
What is healthspan?
The shape/phenotype microglia take when activated
What is ameboid?
This actor is the world's largest nonprofit funder of Parkinson's drug development
Who is Michael J Fox?
The human microbiome project started in this year
What is 2007?
The gut produces what percentage of total body serotonin
What is 90%?
The term that describes the increase in inflammation as we age is
What is Inflammaging?
Two general pathological hallmarks of most neurodegenerative diseases are
What is microglial activation and neuroinflammation?
In "The Lord of the Rings," this creature refers to himself as "the precious."
Who is Gollum?
GI dysfunction occurs in this percentage of PD patients
What is 60-80%?
The neuroglia cell type that removes dead cells and pathogens from the brain
What is microglia?
The loss of this hallmark of aging contributes to imbalances in protein function
What is proteostasis?
The microglia clear what 3 types of pathologic protein aggregates associated with neurodegenerative disease
What is Amyloid-beta, Tau and Alpha-synuclein?
This planet is the home of the Na'vi people in James Cameron's "Avatar."
What is Pandora?
There are 2 million bacterial genes, and this many human genes
What is 20,000?
This cell type regulates neurotransmitter release and directly synapses to the vagus nerve
What are enteroendocrine cells?
Age is the 2nd major factor that affects gut composition, the 1st is
What is "Regional Factors"?
(Country and Continent)
The Microbiome regulates microglial maturation and activation via this molecule type
What are short-chain fatty acids?
In "The Hunger Games," this district is known for its coal mining and is the home of the protagonist, Katniss Everdeen.
What is District 12?
This measures the similarity or dissimilarity of two distinct microbe communities (2 different samples)
What is beta diversity?
(alpha diversity is a measure of microbiome diversity applicable to a single sample, beta diversity is a measure of the similarity or dissimilarity of two communities [different samples])
The connector of epithelial cells in both the gut and brain
What are tight junctions?
This distant relative of microbiota is a key hallmark of aging when dysregulated
What is mitochondria?
(da best ever)
The second most common sporadic neurodegenerative disease
What is Parkinson's disease?
Known for her sideline reporting for NFL Superbowls and iconic American sportscasting, is a famous alumni from the University of Florida
Who is Erin Andrews?