Guillain-Barré Syndrome (GBS)
Comparative MS and GBS
Parkinson’s Disease (PD)
Amyotrophic Lateral Sclerosis (ALS)
100 Points
Comparative PD and ALS
100

What type of motor neuron damage is associated with Guillain-Barré Syndrome?

Damage to the peripheral nervous system caused by demyelination.

100

What is the main difference between MS and GBS in terms of the nervous system affected?

MS affects the central nervous system, while GBS affects the peripheral nervous system.

100

What is the primary neurotransmitter deficit in Parkinson’s Disease?

Dopamine.

100

Which motor neurons are affected in ALS?

Both upper and lower motor neurons.

100

Which condition is primarily associated with motor symptoms and does not typically involve sensory impairments: PD or ALS?

ALS

200

What is the typical progression pattern of weakness in GBS?

Ascending weakness, starting in the lower extremities and moving upward.

200

Which condition is more likely to present with sensory changes like paresthesia: MS or GBS?

Both conditions can present with paresthesia, but it is more common and persistent in MS.

200

What is the hallmark motor symptom often described as a "shuffling gait"?

Bradykinesia, leading to short, shuffling steps.

200

What is a common early symptom of ALS?

Progressive weakness, often starting in the hands or feet.

200

What is the primary difference in the progression of ALS compared to PD?

ALS progresses rapidly and is ultimately fatal, while PD progresses more slowly and is primarily degenerative.

300

During the acute phase of GBS, what should occupational therapy interventions focus on?

Positioning, pain management, and preventing secondary complications.

300

Why is aerobic exercise recommended for clients with MS but cautiously introduced for clients recovering from GBS?

Aerobic exercise can improve overall function in MS, but in GBS, overexertion can worsen symptoms.

300

What intervention can help reduce freezing of gait in Parkinson’s Disease?

Visual or auditory cues, such as stepping over lines or listening to rhythmic beats.

300

What is the focus of occupational therapy during the mid-to-late stages of ALS?

Maximizing function, preserving independence with adaptive equipment, and ensuring caregiver support.

300

How do speech impairments differ between PD and ALS?

In PD, speech is often soft and monotone due to bradykinesia, while in ALS, speech becomes slurred and weak due to muscle weakness.

400

What is a primary goal of occupational therapy during the recovery phase of GBS?

Gradually increasing activity tolerance and restoring functional independence.

400

In MS, which cognitive function is most often affected, and how might an OT address it?

Executive function; OTs can implement memory aids, task sequencing, and environmental modifications.

400

How does rigidity in Parkinson’s Disease present, and what are two types?

Rigidity presents as resistance to passive movement and includes "lead-pipe" and "cogwheel" rigidity. 


400

What is the primary cause of death in most individuals with ALS?

Respiratory failure.

400

Why is early intervention critical in both PD and ALS?

Early intervention maximizes independence, addresses emerging symptoms, and supports long-term planning for progressive impairments.

500

Why is overexertion during therapy contraindicated in clients recovering from GBS?

Overexertion can delay nerve recovery and exacerbate muscle weakness.

500

hat is a common long-term adaptation strategy for both MS and GBS to address fatigue?

Teaching energy conservation techniques, such as prioritizing tasks, delegating, and scheduling rest periods.

500

hat type of exercise has been shown to improve motor and non-motor symptoms in early-stage Parkinson’s Disease?

Intense aerobic exercise.

500

What is the difference between spasticity and flaccidity in ALS, and how does it reflect the progression of the disease?

Spasticity is caused by upper motor neuron damage, while flaccidity results from lower motor neuron damage; both can coexist as the disease progresses.

500

What adaptive equipment might be used for a client with advanced PD versus advanced ALS?

In advanced PD: Weighted utensils to reduce tremors. In advanced ALS: Power wheelchairs for mobility and communication devices for speech loss.