Nerves/Muscles
Autonomic Nervous System
Cholinergic Drugs
Surprise!
Purine/Pyrimidine Synthesis
100
Degeneration of axon distal to injury
What is Wallerian degeneration
100
M1, M2, M3 signal mechanism
What is Gq, Gi, and Gq
100
Muscarinic effects are blocked by muscarinic antagonist drug and has these effects
What is Atropine
What is vasoconstriction and increased blood pressure
100
Missing a UBE3A gene product
What is Angelman Syndrome
100
The formation of this is the first step in purine biosynthesis
It is catalyzed by this enzyme
What is PRPP
What is PRPP Sythetase
200
Targets autoimmune myelin basic protein in the CNS
What is multiple sclerosis
200
Functional cells in the nervous system that contain typical cellular organelles within their cytoplasm
What is neurons
200
This antagonist group and specific drug treats COPD and asthma
What is quaternary ammonium muscarinic antagonist
What is ipratropium
200
Common symptoms of this disease involves microcephaly, macroglossia, umbilical hernia, and abnormal methylation at chromosome 11p15
What is Beckwith-Wiedmann Syndrome
200
This drug inhibits IMP dehydrogenase, which inhibits the conversion of these two products
What is mycophenolic acid (prevents transplant rejection)
What is IMP to GMP
300
Binding affinity increases between myosin head and actin and generates a force as it returns to original position
What is the power stroke
300
Sensory from the spinal cord to the skeletal muscles of the rest of the body
What is somatic efferent
300
Activation of beta 2 and alpha 1 receptors would cause these adverse effects on blood vessels
What vasodilation and vasoconstriction, respectively
300
Both alleles must be affected before malignant transformation can occur
What is tumor suppressor genes
300
Dihydrofolate reductase is competitively inhibited by methotrexate to treat these 3 disease
What are psoriasis, rheumatoid arthritis, and neoplastic diseases
400
400
Chromaffin cells in the adrenal gland releases these (give percentages)
What is 80% epinephrine and 20% norepinephrine
400
Potent inotrope with comparatively mild chronotropic effects and increases myocardial oxygen consumption
What is Dobutamine
400
Without this protein, the MAP Kinase pathway will stay inactive
What is the Ras protein
400
Deficiency in B9 causes these symptoms
What is macrocytic anemia and neural tube defects
500
Label the layers
500
Tyrosine is transported into the adrenergic neuron by system L to produce these neurotransmitters
What is L Dopa, Dopamine, and NE
500
Used for pheochromocytoma prior to surgical removal of tumor
What is phenoxybenzamine
500
Tumor regression results from waves of mutations followed by clonal expansion
What is hyperplastic, metaplastic, dysplastic, neoplastic
500
This anticancer agent is an inhibitor of ribonucleotide reductase and is utilized to decrease this process
What is hydroxyurea
What is DNA replication during cell division