Nuts & Bolts
Drug name with the ® symbol.
What is trade name?
The organ that metabolises drugs the most.
What is the Liver?
The interaction between the drug and the cellular components of the body.
What is drug action?
Used for terminal or end-stage illnesses to ensure the patient's maximum comfort.
What is palliative therapy?
The duration needed between drug administrations to prevent an absorption reaction.
What is 2 hours?
Suspension of microorganism that has been weakened, altered, or killed.
What is vaccine?
The effect that takes place when a drug gets broken down by the liver before entering the bloodstream.
What is the first pass effect?
This drug acts on many different receptors and can lead to many and widespread effects.
What is nonselective drug?
When a patient shows a physical or physiological requirement for a drug.
What is drug dependence?
Often prevents the breakdown of specific drugs, leading to toxic blood levels.
What is grapefruit (juice)?
The name for administration between the teeth and cheek.
What is buccal administration?
The point when absorption rate = elimination rate.
What is the peak concentration of a drug?
The drug's ability to trigger a reaction once it attaches to the receptor.
What is intrinsic activity?
When a patient shows a reduced reaction or diminished response to a drug over time.
What is drug tolerance?
When a patient’s immune system recognizes a drug, drug metabolite, or drug contaminant as a harmful foreign substance to be eliminated or deactivated.
What is drug allerg(y/ic reaction)?
Testing on healthy volunteers during new drug development.
What is phase I of new drug development?
Drugs capable of passing through the blood-brain barrier.
What are lipid soluble drugs?
Attaches to receptor sites and blocks effects of the agonist. The action cannot be reversed by large doses of the agonist.
What is noncompetitive antagonist?
Used for individuals suffering from ongoing, unresolving chronic conditions.
What is maintenance therapy?
When two drugs are taken together and create a stronger effect than if they were taken separately.
What is potentiation or synergistic effect?
Most common special infusion.
What is epidural?
The number of half lives until a drug is eliminated.
What is 4 to 5 half lives?
This drug has a wide range of safety and less risk of toxic effects.
What is drug with a high therapeutic index?
Does not address the root cause of the illness but supports other vulnerable body systems until the patient's condition improves or resolves.
What is supportive therapy?
Reactions that occur in an individual that aren't caused by the drug's expected effects or an allergic reaction, but are unique to that particular person.
What is idiosyncratic response?