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100

Which human organ can regrow to nearly full size even after surgeons remove up to two-thirds of it?

What is the Liver?

100

Who does Patrick Dempsey play in Grey's Anatomy?

Who is Dr. Derek Shepherd?

100

Premiering September 23 on Apple TV, the comedy Brothers stars Woody Harrelson and which fellow Texan, with both playing fictionalized versions of themselves?

Who is Matthew McConaughey?

100

Who did George Washington name as vice president?

Who is John Adams?

100

“In West Philadelphia, born and raised…” is the opening to this ‘90s sitcom theme.

What is Fresh Prince of Bel-Air?

200

How many teaspoons are in a tablespoon?

What are 3?

200

Which “That ‘70s Show” actor plays the role of a florist in the 2010 movie “Valentine’s Day”?

Who is Ashton Kutcher?

200

At the recent MTV Video Music Awards, which grunge band received the Video Vanguard Award, with Dave Grohl and wife Jordyn Blum making a rare joint appearance?

What is Nirvana?

200

Who was both the 22nd and the 24th president of the United States?

Who is Grover Cleveland?

200

This long-running animated show begins with a couch gag after its theme by Danny Elfman.

What are The Simpsons?

300

During a 2016 augmented-reality craze, what mobile game sent millions hunting virtual creatures across city parks?

What is Pokémon GO?

300

Who voiced Rocky in the movie "Chicken Run"?

Who is Mel Gibson?

300

At Connect 2026, Mark Zuckerberg unveiled Charm, a keychain-sized gadget for chatting with what personal AI agent Meta launched earlier in September?

What is Muse?

300

Which organization was awarded the Nobel Peace Prize in 1917?

What is Red Cross?

300

This show’s jazzy theme is famously performed on a bass guitar and has no lyrics, just a snapping beat and finger clicks.

What is The Addams Family?

400

Nintendo's flagship character Mario first appeared as "Jumpman" in what iconic arcade game?

What is Donkey Kong?

400

The 1997 movie "Dante's Peak" tells the story of a town that is threatened by what?

What is A volcano?

400

Kicking more than 11,000 feet above sea level in Switzerland on September 22, which Hall of Fame former Patriots kicker set a Guinness record for the highest-altitude field goal?

Who is Adam Vinatieri?

400

Which U.S. state was the last to join the Union in 1959?

What is Hawaii?

400

The lyrics “Thank you for being a friend…” kick off this iconic 1980s sitcom.

What is The Golden Girls?

500

What rank in the US Army is just above the rank of First Lieutenant?

What is Captain?

500

In the 2014 computer-animated film The LEGO Movie, which actor voices Emmet Brickowski?

Who is Chris Pratt?

500

The NFL played its first regular-season game in Rio de Janeiro on September 27, when the Cowboys and Ravens squared off at what iconic stadium?

What is Maracanã Stadium?

500

Where was the U.S. Contitutional Convention held?

What is Philadelphia, Pa?

500

This show featured a theme song by Jan Hammer that became a Billboard hit.

What is Miami Vice?

600

Who was the first winner of the Fifa World Cup?

What is Uruguay?

600

Known for over-the-top explosions, which filmmaker made his feature debut directing Bad Boys?

Who is Michael Bay?

600

"Britain is back," declared which new British prime minister in his first UN General Assembly address on September 22?

Who is Andy Burnham?

600

What was the name of the Mayflower's sister ship?

What is Speedwell?

600

“Way down in the jungle deep…” was the original intro line to this underground comedy sketch series that launched in 2003.

What is Chappelle’s Show?

800

Who did sports fans know as "the Wizard of Westwood"?

Who is John Wooden?

800

What was the first TV kids show in the US?

What is Howdy Doody Show?

800

On September 26, hundreds of thousands packed the Champs-Élysées for an outdoor Mass celebrated by which pope?

Who is Pope Leo XIV? (13)

800

The Opium Wars were fought between China and which European power?

What is Great Britain?

800

This theme features haunting piano music and the iconic sound of a ticking stopwatch.

What is Lost?

1000

What 1843 Dickens novel ends with the line, "And so, as Tiny Tim observed, God bless us, every one!"

What is a Christmas Carol?

1000

Which artist recorded the Christmas song "Run Rudolph Run" in 1958?

Who is Chuck Berry?

1000

What Kane Parsons horror film, A24's highest-grossing release, began streaming on HBO Max on September 25?

What is Backrooms?

1000

What captain of the American Revolution is considered to be the father of the US Navy?

Who is John Paul Jones?

1000

The theme song “Angela” by Bob James is associated with this late 70s/early 80s sitcom.

What is Taxi?