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ACT 1
ACT 2
I Object!
Fill in the blank
100
nVNS
what is non-invasive vagus nerve stimulation
100
The treatment regimen
What is three 2-minute stimulations at the onset of pain
100
major side effects of gammaCore therapy
What is none?
100
Dr. Smith: "Vagus nerve stimulation can affect the cardiovascular system; I worry this could adversely affect my patient's cardiac health"
What is gammaCore only stimulates the A and B fibers; not the C fibers which enervate the heart.
100
gammaCore is clinically proven to provide ___________, ___________ and ___________ pain relief.
What is fast, sustained and reliable
200
Tagline
what is Activate Relief from the Outside in
200
Total number of patients enrolled
What is 150?
200
Primary end point
What is percentage of total attacks that were pain-free 15 minutes after treatment started
200
Dr. Jones: "gammaCore did not do well for chronic cluster patients in Act I and Act II"
What is chronic disease states are notoriously more difficult to treat. Theory: the threshold of pain is higher in chronic patients; it might take a longer treatment period to get results in chronic which wasn't possible to see in the design of ACT 1 and ACT 2
200
__________, _____________ and ________, gammacore is about the size of a cell phone.
What is portable, convenient and hand-held
300
Indication
What is acute treatment of pain associated with episodic cluster headache in adult patients
300
Primary endpoint
What is the percentage of patients reporting mild or no pain 15 minutes after treatment started?
300
What is the treatment regimen
What is three 2-minute stimulations at the onset of pain, wait 3 minutes, if pain persists treat with an addiitonal three 2-minute stimulations
300
Dr. Green: "Cefaly has a money back guarantee, which helps for patients to try the device. gammaCore should have the same policy"
What is Yes, we agree. GPR allows eCh patients to receive 2 free devices in return for participating in our registry program. One month free trial with our next generation Sapphire device will also be offered to patients in the near future.
300
gammacore sends __________, ___________ ____________ stimulaiton through the skin to non-invasively activate the vagus nerve.
What is gentle, patented electrical
400
TAC
What is Trigeminal Autonomic Cephalalgia
400
nVNS 34.2%, sham 10.6%
What is the episodic cluster headache cohort result?
400
nVNS 47.5%, sham 6.2%
What is the episodic cluster headache cohort result?
400
Dr. White: "I don’t have an issue with my Cluster patients; my patients are satisfied with their current treatment"
What is No they aren't! 291 Surveyed patients stated they were not satisfied with current acute treatments and felt there was a need for new, safer treatments
400
gammaCore avoids many drug-like side effects and no need for ___________, ____________ and __________ medication.
What is injecting, inhaling and ingesting
500
Rule of "3s"
What is 3 two-minute doses, wait 3 minutes, 3 more two-minute doses. (also refers to 1. Prepare for a dose, 2. Start the dose and 3. Deliver the dose)
500
Three adjectives describing the clinical study
What is randomized, double-blind, sham-controlled
500
Percentage of attacks eCH patients successfully treated
What is >50%
500
Dr. Oz: "gammaCore is too expensive, my patients can’t afford it, and it’s not covered by their insurance."
What is gammaCore is priced similarly to the current standard of care. Triptans cost $100 per injection and insurance often limits patients to 6 injections per month. For the same cost, patients can treat up to 4 attacks daily with gammaCore. Insurance policies are being updated as we speak.
500
Safety and efficacy of gammaCore has not been evaluated in the following patients and is therefore NOT indicated for patients with__________, ______________ or ___________
What is an active implanted medical device, narrowing of the arteries, cervical vagotomy? (also acceptable: Pregnant, pediatrics, metallic device near the neck, significant ongoing clinical cardiac history.)